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Orthopedics

Metformin reverses impaired osteogenesis due to hyperglycemia-induced neutrophil extracellular traps formation.

Sep 04, 2023

Diabetic patients suffer from delayed fracture healing and impaired osteogenic function, but the underlying pathophysiological mechanisms are not fully understood. Neutrophil extracellular traps (NETs...

Indices for the brittleness of pharmaceutical tablets: a reassessment.

Sep 04, 2023

Brittleness is an important mechanical property. In the classical sense, a material is considered brittle if, during loading, it behaves elastically until failure. Nevertheless, it is also sometimes u...

Functional Hypothalamic Amenorrhea: Recognition and Management of a Challenging Diagnosis.

Sep 04, 2023

Functional hypothalamic amenorrhea is responsible for approximately a third of the cases of secondary amenorrhea. The condition is a result of disturbances in gonadotropin-releasing hormone pulsatile ...

Total Hip Arthroplasty Can Be Performed Safely in 90-Year-Olds

Sep 01, 2023

THURSDAY, Aug. 31, 2023 (HealthDay News) -- While 90-year-olds undergoing elective total hip arthroplasty (THA) have higher complication and mortality rates than younger patients undergoing THA, their...

Most Fish Oil Supplement Labels Make Health Benefit Claims

Aug 28, 2023

FRIDAY, Aug. 25, 2023 (HealthDay News) -- The majority of fish oil supplement labels make health claims and vary significantly in the recommended daily dosage, according to a study published online Au...

Influence of stem design parameters on periprosthetic femoral fractures examined by subject specific finite element analyses.

Aug 28, 2023

Due to the increasing number of periprosthetic femoral fractures (PFF), the optimisation of implant design gains importance. For the presented research a validated, subject specific finite element mod...

The role of the depth of resection of the distal tibia on biomechanical performance of the tibial component for TAR: A finite element analysis with three implant designs.

Aug 28, 2023

The depth of resection of the tibia bone in total ankle replacement (TAR) may influence implant-bone micromotion and stress shielding. High implant-bone micromotion and stress-shielding lead to asepti...

Analysis and multiple index evaluation of SPO distribution of bone traction needles for pelvic fracture reduction.

Aug 28, 2023

For robot-assisted pelvic fracture reduction, at least two bone needles need to be inserted into the ilium of the affected pelvis, and the robot clamping device is connected with the bone needles. The...

App Beneficial for Management of Adolescent Idiopathic Scoliosis

Aug 25, 2023

THURSDAY, Aug. 24, 2023 (HealthDay News) -- A deep learning application (app) model using a smartphone photograph is useful for management of adolescent idiopathic scoliosis (AIS), according to a stud...

Cast Immobilization Comparable to Surgery for Distal Radius Fractures in Elderly

Aug 25, 2023

THURSDAY, Aug. 24, 2023 (HealthDay News) -- For older adults, cast immobilization (CI) performs similarly to surgical therapies for distal radius fractures (DRFs) at one year postoperatively, accordin...

EASD: Factors Linked to Lower-Limb Amputation ID'd in Diabetes

Aug 24, 2023

WEDNESDAY, Aug. 23, 2023 (HealthDay News) -- For people with newly diagnosed diabetes, the risk for lower-limb amputation (LLA) is increased for those with older age, males, and divorced individuals, ...

Bilateral Total Knee Arthroplasty Tied to Higher Complication Rates

Aug 23, 2023

TUESDAY, Aug. 22, 2023 (HealthDay News) -- Simultaneous bilateral total knee arthroplasty (TKA) is associated with increased rates of complications, according to a study published in the July 19 issue...

7.6 Percent of Global Population Had Osteoarthritis in 2020

Aug 23, 2023

TUESDAY, Aug. 22, 2023 (HealthDay News) -- The global burden of osteoarthritis has increased since 1990 and is projected to continue increasing, according to a study published online Aug. 21 in The La...

Hip fracture surgery performed by cadaveric simulation-trained versus standard-trained orthopaedic trainees: a preliminary multicentre randomized controlled trial.

Aug 21, 2023

To evaluate if, for orthopaedic trainees, additional cadaveric simulation training or standard training alone yields superior radiological and clinical outcomes in patients undergoing dynamic hip scre...

Assessing the risk of re-fracture related to the percentage of partial union in scaphoid waist fractures.

Aug 21, 2023

There is ambiguity surrounding the degree of scaphoid union required to safely allow mobilization following scaphoid waist fracture. Premature mobilization could lead to refracture, but late mobilizat...

"Geriatric Proximal Humerus Fracture Operative Management: A TRUVEN Health Analytics Database Study (2015-2020)".

Aug 14, 2023

The purpose of this study is to assess the trends in operative management of geriatric (≥65 years) proximal humerus fractures during a six-year period (2015-2020) within an insurance claims database...

Understanding Exercise Capacity - from Elite Athlete to HFpEF.

Aug 14, 2023

Exercise capacity is a spectrum which reflects an individual's functional capacity and the dynamic nature of cardiac remodeling along with respiratory and skeletal muscle systems. The relationship bet...

Bone-Targeted Delivery of Cell-Penetrating-RUNX2 Fusion Protein in Osteoporosis Model.

Aug 14, 2023

The onset of osteoporosis leads to a gradual decrease in bone density due to an imbalance between bone formation and resorption. To achieve optimal drug efficacy with minimal side effects, targeted dr...

Hip Fracture Risk Higher Among Vegetarians Versus Regular Meat Eaters

Aug 10, 2023

TUESDAY, Aug. 8, 2023 (HealthDay News) -- Vegetarians have a higher risk for hip fracture than regular meat eaters, according to a study published online July 27 in BMC Medicine.James Webster, from th...

Surgical Stabilization Beneficial for Odontoid Fractures

Aug 10, 2023

WEDNESDAY, Aug. 9, 2023 (HealthDay News) -- For patients with odontoid fractures, surgical stabilization is associated with a reduced rate of nonunion and mortality at 30 days and one year, according ...

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