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Orthopedics

An Adjunct Indicator for the Diagnosis of Fracture-Related Infections: Platelet Count to Mean Platelet Volume Ratio.

May 28, 2020

Fracture-related infection (FRI) is a common complication associated with orthopaedic fracture care. Diagnosing these complications in the preoperative setting is difficult. Platelets are a known acu...

The effects of vitamin K-rich green leafy vegetables on bone metabolism: A 4-week randomised controlled trial in middle-aged and older individuals.

May 28, 2020

High vegetable intake is associated with beneficial effects on bone. However, the mechanisms remain uncertain. Green leafy vegetables are a rich source of vitamin K1, which is known to have large effe...

Gnathodiaphyseal dysplasia is not recapitulated in a respective mouse model carrying a mutation of the Ano5 gene.

May 28, 2020

Mutations in the gene , encoding for the transmembrane protein Anoctamin 5 (Ano5), have been identified to cause gnathodiaphyseal dysplasia (GDD) in humans, a skeletal disorder characterized by sclero...

Hydroxyethyl Chitosan-Reinforced Polyvinyl Alcohol/Biphasic Calcium Phosphate Hydrogels for Bone Regeneration.

May 28, 2020

Fabrication of reinforced scaffolds for bone regeneration remains a significant challenge. The weak mechanical properties of the chitosan (CS)-based composite scaffold hindered its further application...

Primary stability and healing outcomes of apically tapered and straight implants placed into fresh extraction sockets. A pre-clinical in vivo study.

May 28, 2020

To compare the stability of apically tapered and straight (non-tapered cylindrical) implants at the time of immediate placement and to histologically evaluate the healing outcomes after 6 weeks.The se...

Characteristics of three different patellar implant designs in total knee arthroplasty.

May 28, 2020

Despite debate over the role of patellar resurfacing in total knee arthroplasty, many surgeons feel it decreases re-operation rates and anterior pain, and an increasing number are adopting resurfacing...

Surgery Not Superior for Closed Displaced Humeral Shaft Fractures

May 27, 2020

WEDNESDAY, May 27, 2020 (HealthDay News) -- Internal fixation surgery to treat closed humeral shaft fracture does not significantly improve 12-month outcomes versus nonoperative functional bracing, ac...

Only One in Four U.S. Hospitals With ICUs Have Tele-ICU Services

May 27, 2020

WEDNESDAY, May 27, 2020 (HealthDay News) -- In 2018, half of U.S. hospitals had the capacity to conduct telehealth-based outpatient visits, while only one in four had tele-intensive care unit (tele-IC...

Dental Injuries at the Xi'an, China Stomatological Hospital: A Retrospective Study.

May 26, 2020

In order to enrich epidemiological knowledge regarding traumatic dental injuries (TDI) in China, and to further improve the treatment, prevention and education of TDI, the aim of this study was to ret...

Intraprocedural Ergonomics of Vascular Surgeons.

May 26, 2020

to estimate the ergonomic postural risk for musculoskeletal posture of vascular surgeons performing open and endovascular procedure types and with various adjunctive equipment using wearable inertial ...

Trabecular bone score and transilial bone trabecular histomorphometry in type 1 diabetes and healthy controls.

May 26, 2020

Patients with type 1 Diabetes Mellitus (T1DM) have an increased risk of fracture. Little is known about the microarchitecture of trabecular bone in T1DM, which may account for some of the increased ri...

Cortical thinning and accumulation of large cortical pores in the tibia reflect local structural deterioration of the femoral neck.

May 26, 2020

Cortical bone thinning and a rarefaction of the trabecular architecture represent possible causes of increased femoral neck (FN) fracture risk. Due to X-ray exposure limits, the bone microstructure is...

Acute Total Knee Replacement in Rheumatoid Arthritis Patients with Proximal Tibial Fractures: A Case Series.

May 26, 2020

Management of proximal tibial fractures is a challenging issue in patients with rheumatoid arthritis (RA). In the present study, we aimed to describe our experience of acute total knee replacement in ...

A CRISPR-engineered swine model of COL2A1 deficiency recapitulates altered early skeletal developmental defects in humans.

May 26, 2020

Loss-of-function mutations in the COL2A1 gene were previously described as a cause of type II collagenopathy (e.g., spondyloepiphyseal dysplasia, Stickler syndrome type I), a major subgroup of genetic...

Surface modified and activated waste bone char for rapid and efficient VOCs adsorption.

May 26, 2020

In this work, very efficient VOCs adsorbent was developed from waste bovine bone. After pyrolysis at 450 °C, the bone char was treated by HPO for surface modification and activated by KCO respective...

Heterotopic Transplantation of Allogeneic Vertical Rectus Abdominis Myocutaneous Flaps in Miniature Swine.

May 26, 2020

Vascularized composite tissue allotransplantation (VCA) opens new possibilities for reconstruction of complex tissue defects, including upper extremity and facial transplantation. The main challenges ...

Inhibitory effect of the TSG-6 on the BMP-4/Smad signaling pathway and odonto/osteogenic differentiation of dental pulp stem cells.

May 26, 2020

This study aimed to observe the molecular mechanism underlying the effect of tumor necrosis factor-inducible protein 6 (TSG-6) on the bone morphogenetic protein-4 (BMP-4)/drosophila mothers against de...

Classic and targeted anti-leukaemic agents interfere with the cholesterol biogenesis metagene in acute myeloid leukaemia: Therapeutic implications.

May 26, 2020

Despite significant advances in deciphering the molecular landscape of acute myeloid leukaemia (AML), therapeutic outcomes of this haematological malignancy have only modestly improved over the past d...

Biomechanical Footwear May Aid Knee Osteoarthritis Outcomes

May 23, 2020

FRIDAY, May 22, 2020 (HealthDay News) -- Use of biomechanical footwear is associated with an improvement in pain among patients with knee osteoarthritis at 24 weeks of follow-up, although the improvem...

Lower Physical Function Prior to TKA Predictive of Outcomes Among Black Women

May 18, 2020

WHI cohort study suggests focusing on optimizing physical functioning before surgery Lower levels of physical function (PF) before total knee arthroplasty (TKA) may help explain why black women have ...

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