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Erectile Dysfunction Urology

In-silico and in-vivo evaluation of sesamol and its derivatives for benign prostatic hypertrophy.

Sep 06, 2021

Pharmacological treatment for BPH includes 5- reductase inhibitors as Finasteride and Dutasteride as a monotherapy or in combination with antimuscarinic drugs, alpha-blockers, 5-phosphodiesterase inhi...

A case report of pudendal arteries angioplasty with sirolimus drug-coated balloon and drug-eluting stent associated with intracavernous autologous peripheral blood mononuclear cells injection for untreatable vasculogenic erectile dysfunction.

Aug 23, 2021

Erectile dysfunction (ED) is a prevalent health problem that seriously impacts men's quality of life. The potential treatment of ED by percutaneous approach has emerged with valid angiographic results...

Incidence of Venous Thromboembolism and Safety of Perioperative Subcutaneous Heparin During Inflatable Penile Prosthesis Surgery.

Aug 23, 2021

To identify the incidence of venous thromboembolism (VTE) risk factors, postoperative VTE, and to assess the morbidity of perioperative pharmacologic VTE prophylaxis in men undergoing inflatable penil...

Pornography Addiction: An Exploration of the Association Between Use, Perceived Addiction, Erectile Dysfunction, Premature (Early) Ejaculation, and Sexual Satisfaction in Males Aged 18-44 Years.

Aug 19, 2021

The way men consume pornography changed over the last decade, with increased numbers of men presenting with self-perceived Internet pornography (IP) addiction and related sexual dysfunction. A lack of...

Impact of the SARS-CoV-2 Virus on Male Reproductive Health.

Aug 19, 2021

The Coronavirus 2019 (COVID-19) pandemic caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to more than 160 million infections and 3.5 million deaths globally. M...

Could erectile dysfunction be a side effect of CGRP inhibition? A case report.

Aug 19, 2021

Recently, antimigraine drugs targeting the calcitonin gene-related peptide pathway have been approved for clinical use as preventive migraine medication.We present a case of a 54-year-old male migrain...

Advances in Nanoparticle Delivery System for Erectile Dysfunction: An Updated Review.

Aug 16, 2021

The use of current available treatment for male erectile dysfunction (ED) has some limitations that are related to efficacy and adverse effects. Nanotechnology has been used as a new tool in medicine ...

Cardiovascular Outcome Risks in Patients With Erectile Dysfunction Co-Prescribed a Phosphodiesterase Type 5 Inhibitor (PDE5i) and a Nitrate: A Retrospective Observational Study Using Electronic Health Record Data in the United States.

Aug 16, 2021

Phosphodiesterase type 5 inhibitors (PDE5i) are first-line therapy for erectile dysfunction (ED). Approximately 1-4% of PDE5i recipients co-possess nitrates, despite this combination potentially produ...

Influence of anticancer agents on sexual function: an in Vivo study based on the US FDA Adverse Event Reporting System.

Aug 16, 2021

Patients with cancer are treated with chemotherapeutics that cause adverse effects, including erectile dysfunction (ED).We investigated erectile function in rats after the administration of anticancer...

Complete study for erectile dysfunction (CompED) improving diagnosis and treatment decision-making.

Aug 12, 2021

Erectile dysfunction is a condition associated with increasing age. Patient evaluation and management should follow a comprehensive, stepwise approach. The aim of this article was to report our experi...

Epidemiology and aetiology of male and female sexual dysfunctions related to pelvic ring injuries: a systematic review.

Aug 12, 2021

Pelvic ring injuries, frequently caused by high energy trauma, are associated with high rates of morbidity and mortality (5-33%), often due to significant blood loss and disruption of the lumbosacral ...

Influence of Lisdexamfetamine Dimesylate on Early Ejaculation-Results from a Double-Blind Randomized Clinical Trial.

Aug 09, 2021

Among male sexual dysfunctions, erectile dysfunction and early ejaculation have the highest prevalence rates. Here, we tested the influence of lisdexamfetamine dimesylate (Vyas) on early ejaculation. ...

An Overview of NO Signaling Pathways in Aging.

Aug 09, 2021

Nitric Oxide (NO) is a potent signaling molecule involved in the regulation of various cellular mechanisms and pathways under normal and pathological conditions. NO production, its effects, and its ef...

RNA-sequencing profiling analysis of pericyte-derived extracellular vesicle-mimetic nanovesicles-regulated genes in primary cultured fibroblasts from normal and Peyronie's disease penile tunica albuginea.

Aug 09, 2021

Peyronie's disease (PD) is a severe fibrotic disease of the tunica albuginea that causes penis curvature and leads to penile pain, deformity, and erectile dysfunction. The role of pericytes in the pat...

Prospective analysis over time of semen parameters in spinal cord-injured patients: results of a pilot study.

Aug 05, 2021

Spinal cord injury (SCI) often results in erectile dysfunction and anejaculation along with impaired semen parameters. Fertility is a major concern in SCI adult males and some fear that the delay post...

Comorbidities Among Sexual Problems in Men: Results From an Internet Convenience Sample.

Aug 05, 2021

Men suffering from one sexual problem sometimes report having another sexual problem, but few studies have determined concordance rates among dysfunctions in non-clinical samples.This study determined...

Safety of autologous bone marrow-derived mesenchymal stem cells in erectile dysfunction: an open-label phase 1 clinical trial.

Aug 02, 2021

The efficacy of phosphodiesterase type 5 inhibitors (PDE5Is), which are commonly used to treat erectile dysfunction (ED), is not satisfactory in patients with denervation of the cavernous nerve due to...

Culture and purification of SD rat corpus cavernosum endothelial cells by enzymatic digestion combined with mechanical extrusion and fixed-point digestion.

Aug 02, 2021

To explore a new method of in vitro culture and purification of rat corpus cavernosum endothelial cells (CCECs). Male Sprague-Dawley rats' penile tissue were digested with elastase or collagenase comb...

Interactions between erectile dysfunction, cardiovascular disease and cardiovascular drugs.

Aug 02, 2021

Sexual health has a fundamental role in overall health and well-being, and a healthy and dynamic sex life can make an important contribution to a good quality of life. Sexual dysfunction, and especial...

Radical cystectomy and orthotopic neobladder in a patient with a preexisting three-components inflatable penile prosthesis.

Jul 29, 2021

As erectile dysfunction is more commonly being diagnosed and treated with a preexisting inflatable penile prosthesis (IPP) insertion at younger ages, surgeons will increasingly encounter pre-placed ab...