This invited editorial celebrates the distinguished professional life of Professor Kevin D. Tipton, who sadly passed away on January 9, 2022. Professor Tipton made an outstanding contribution to the scientific field of sport nutrition and exercise metabolism over an exceptional 30-year career. He dedicated his academic career to understanding the response of muscle protein metabolism to exercise and nutrition. The impact of his work is far-reaching with application to athletes in terms of promoting training adaptation, recovery, and performance, alongside clinical implications for injury management and healthy aging. Notable scientific contributions included the first in vivo human study to demonstrate the role of orally ingested essential amino acids in stimulating muscle protein synthesis during acute post-exercise recovery. This finding laid the foundation for future studies to interrogate the response of muscle protein synthesis to the ingestion of different protein types. Professor Tipton’s work also included investigating the maximally effective dose and timing (regarding exercise) of ingested protein for the stimulation of muscle protein synthesis. Kevin will be remembered fondly by academics, applied scientists, and students across the sport nutrition and exercise metabolism community as a leading researcher in the field, a critical thinker, and an inspirational teacher. His mission was to educate the next generation of exercise scientists by sharing his distinct wealth of knowledge accrued over three decades. Above all else, Kevin was kind, generous (with his time and knowledge), honest, and incredibly social. He was a unique character and will be greatly missed among our community but certainly never forgotten.