The right ventricle (RV) is uncommonly implicated in post-infarction ventricular tachycardia (VT). The prevalence and features of RV substrate participating in post-infarction VT are undefined.
To characterize critical RV substrate (CRVS) involvement in patients with post-infarction VT.
We retrospectively reviewed 1279 patients with post-infarction VT undergoing catheter ablation at our center from January 2000 through May 2020. Cases with CRVS defined by conclusive demonstration of participation in VT with activation, entrainment and/or pace mapping during sinus rhythm were identified.
CRVS was identified in 27/1279 (2.1%), age 65±13 years, 96% males, median LV EF 25%, 93% with LBBB morphology VT. CRVS was identified by RV activation and/or entrainment mapping (n=19) or by presence of low-voltage abnormal electrograms with excellent pace-map for the targeted VT and non-inducibility following ablation (n=8). VT termination during RV ablation occurred in 15 patients. After a median follow-up of 20 months (interquartile range 9-53 months) and a median of 2 procedures (interquartile range 1-3), 22/27 (80%) patients had no VT recurrence and 11 (41%) died.
The RV contains critical substrate elements of post-infarction VT in at least 2.1% of cases. RV mapping should be considered in cases where LV mapping fails to demonstrate adequate targets, particularly in patients with LBBB morphology VT.

Copyright © 2022. Published by Elsevier Inc.

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