To investigate the role of nurse-led, goal-directed lung physical therapy on the prognosis of patients with sepsis caused by Acinetobacter baumannii pulmonary infection.
Patients with sepsis caused by A. baumannii pulmonary infection were recruited and divided into an observational group (phase 1) and treatment group (phase 2). Both groups received standard therapy for sepsis, and patients in phase 2 also received nurse-led, goal-directed lung physical therapy.The primary outcome measure was 28-day mortality.
Among 742 septic patients, 201 were diagnosed with A. baumannii pulmonary infection. Compared with patients in phase 1, the patients in phase 2 had a significantly lower MV duration [days: 4 (3,5) vs. 5 (3,12), p = 0.004 ], ICU mortality [13.6% (18/132) vs. 27.5% (19/69), p = 0.016], and 28-day mortality[21.2% (28/132) vs.37.7% (26/69), p = 0.012]. As a protective factor, nurse-led, goal-directed lung physical therapy (OR 0.341, 95% CI, 0.155-0.751, p = 0.008) was an independent risk factor of 28-day mortality.
Nurse-led, goal-directed lung physical therapy shortened MV duration and ICU stay, and decreased ICU and 28-day mortality in patients with sepsis caused by A. baumannii pulmonary infection.
Copyright © 2020. Published by Elsevier Ltd.