Lymph node dissection(LND) remains the gold standard in the staging and treatment of locally advanced penile cancer(PC).
To describe our initial experience with a new minimally invasive inguinal and pelvic single-access laparoscopic approach,for performing LND in PC, first described in Urology by our group in 2015: the Pelvic and Inguinal Single Access(PISA) technique (Figure 1).
Between 2015-2018, 10 consecutive patients with different PC stages and indication of inguinal LND (cN0 and ≥pT1G3 or cN1/cN2) were operated by means of the PISA technique (Table 1). Intraoperative frozen section(FS) analysis was carried out routinely and if ≥2 inguinal nodes(pN2) or extracapsular nodal extension(pN3) are detected, ipsilateral pelvic LND was performed sequentially as a single-stage procedure and using the same surgical incisions. If this condition occurs bilaterally in the inguinal LND, the pelvic LND will be bilateral. The video shows the PISA technique in a step-by-step.Instrumental requirements:30°laparoscopy optic, monopolar scissors,Ligasure (Covidien Surgical®,Minneapolis,MN,USA) vascular sealant, extraction-bag, bipolar forceps and 5-mm endo-clip(Hem-o-lok®)are required.
Intraoperative and postsurgical variables are shown in table 2. Inguinal LND was bilateral in all cases. Pelvic LND was required in 40% of patients. Total operative time was 120-170 minutes. Median estimated blood loss(EBL) was 66(30-100)cc, but no blood transfusion was required. No intraoperative complications were noted. 40% of patients had postoperative complications (10% major complication- symptomatic inguinal lymphocele). Median lenght of hospital stay(LOS)was 5.8(3-10) days. Median inguinal drain removal was 4.7 days. The pathological analysis outcomes are shown in table 3. Mean number of lymph nodes removed by inguinal LND was 10.25(8-14).
PISA technique allow a minimally invasive inguinal and pelvic LND using the same set of incisions and carry it out in the same surgical procedure. PISA technique in PC LND seems to be safe, with a low rate of major complications and preserving oncological efficacy.

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