Mechanical circulatory support systems (MCSSs) are crucial devices for transplants in patients with heart failure. The blood flowing through the MCSS can be recirculated or even stagnated in the event of critical blood flow issues. To avoid emergencies due to abnormal changes in the flow, continuous changes of the flowrate should be measured with high accuracy and robustness. For better flowrate measurements, a more advanced ultrasonic blood flowmeter (UFM), which is a noninvasive measurement tool, is needed. In this paper, we propose a novel UFM sensor module using a novel algorithm (Xero) that can exploit the advantages of both conventional cross-correlation (Xcorr) and zero-crossing (Zero) algorithms, using only the zero-crossing-based algorithm. To ensure the capability of our own developed and optimized ultrasonic sensor module for MCSSs, the accuracy, robustness, and continuous monitoring performance of the proposed algorithm were compared to those of conventional algorithms after application to the developed sensor module. The results show that Xero is superior to other algorithms for flowrate measurements under different environments and offers an error rate of at least 0.92%, higher robustness for changing fluid temperatures than conventional algorithms, and sensitive responses to sudden changes in flowrates. Thus, the proposed UFM system with Xero has a great potential for flowrate measurements in MCSSs.
Copyright © 2021. Published by Elsevier B.V.

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