Perceived health is one of the strongest determinants of subjective well-being, but it has received little attention among survivors of acute respiratory distress syndrome (ARDS).
How well do self-reported measures of physical, emotional, and social functioning predict perceived overall health (measured using the EQ-5D visual analogue scale (EQ-5D-VAS)) among adult ARDS survivors? Are demographics, comorbidity, or severity of illness correlated with perceived health after controlling for self-reported functioning?
We analyzed ALTOS and ICAP, two longitudinal cohorts with a total of 823 survivors from 44 U.S. hospitals, which prospectively assessed survivors at 6 and 12 months after ARDS. Perceived health, evaluated using the EQ-5D-VAS, was predicted using ridge regression and self-reported measures of physical, emotional, and social functioning. The difference between observed and predicted perceived health was termed “perspective deviation” (PD). Correlations between PD and demographics, comorbidities, and severity of illness were explored.
The correlation between observed and predicted EQ-5D-VAS scores ranged from 0.68 to 0.73 across the 2 cohorts and time points. PD ranged from -80 to +34 and was greater than the minimal clinically important difference for 52%-55% of survivors. Neither demographics, comorbidity, nor severity of illness were strongly correlated with PD with |r|<0.25 for all continuous variables in both cohorts and time points. The correlation between PD at 6 and 12 month assessments was weak (ALTOS: r = 0.22, P<0.001; ICAP: r = 0.20, P=0.02).

Copyright © 2021. Published by Elsevier Inc.