The aim: To conduct an analysis of the complex treatment of severe forms of rectal abscesses complicated by NF.Materials and methods: The results of treatment in 471 patients with deep forms...
Despite being crucial for combating microbes, paradoxical Toll-like receptors (TLRs) signaling have been associated with the aggravation of multiple immune disorders such as systemic lupus e...
This study was aimed at investigating the regulation of mitochondrial function by histone deacetylase 6 (HDAC6) and the role of HDAC6 in the development and progression of sepsis.HDAC6 downr...
Long non-coding RNA (lncRNA) cancer susceptibility candidate 9 (CASC9) is reported to be linked to cancers. This research aims to explore the role and possible mechanism of CASC9 in lung inj...
Laboratory diagnostics are essential for diagnosis, initiation of therapy, and monitoring of patients. Laboratory results that are overlooked or incorrectly interpreted lead to adverse event...
![[Improved patient safety through a clinical decision support system in laboratory medicine].](https://www.physiciansweekly.com/wp-content/uploads/2023/08/Intensive-critical-care-patient-room-ICU-3-e1707944022882.jpg)
Evidence indicates that the use of severe sepsis and septic shock (SS/SS) treatment bundles is associated with lower mortality when compared with no use. However, delivering successful SS/SS...
Osteopontin (OPN) is evolving as a novel biomarker of injury, overall survival and renal outcome in critically ill patients with acute kidney injury (AKI), requiring renal replacement therap...
To determine if vitamin D status is affected in term neonates with early onset sepsis and its association with outcome.Study was done at a level 3 neonatal unit on 140 neonates. Term neonate...
Collagen and fibrin engagement and activation of glycoprotein (GP) VI induces proteolytic cleavage of the GPVI ectodomain generating shed soluble GPVI (sGPVI). Collagen-mediated GPVI sheddin...
Untreated sludge from small-scale on-site domestic wastewater treatment systems (septic tanks) was spiked with 20, 60 and 100 nm silver nanoparticles (Ag-NPs) to investigate Ag-NP behaviou...
Recommended time to start administration of first dose antibiotics for sepsis patients is 60 minutes from time 0. Institution-specific data revealed that only one-quarter of severe sepsis pa...
Esophageal perforations are difficult to diagnose and have a high mortality rate. Cervical esophageal perforations (CEPs) are the second most common anatomic type of esophageal perforations ...
To investigate methods of antibiotic duration minimization and their effect on mortality and infectious complications in critically ill patients.A systematic search of PubMed, Embase (via Ov...
Background Timely diagnosis of pediatric sepsis remains elusive. We estimated the risk of potentially missed pediatric sepsis in US emergency departments (EDs) and determined factors associa...
Investigate 25-hydroxy vitamin D (25(OH)D) levels and the correlation with cardiovascular sequential organ failure assessment (CV-SOFA) and pediatric risk of mortality III (PRISM-III) score...
This work aims to investigate the function and mechanism of long non-coding RNA (lncRNA) cytoskeleton regulator RNA (CYTOR) in myocardial injury induced by sepsis. The sepsis-induced myocard...
Platelets have the highest bacterial contamination risk of all blood components, and septic transfusion reactions remain a problem. A good estimate of contamination rates could provide infor...
To determine if baseline lipid levels contribute to the relationship between lipid levels during sepsis and outcomes.We conducted a retrospective cohort study at a tertiary-care academic med...
This study evaluated the impact of a dedicated outpatient service on vaccination uptake after splenectomy and on the incidence of postsplenectomy sepsis.From 2009 to 2016 at the University H...
Cost evaluation is a key tool in monitoring expenditure for budget management. It increases the efficiency of possible changes through identifying potential savings and estimating the resour...
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