Advertisement

Brain Cancer Oncology

A Brief History of Machine Learning in Neurosurgery.

Dec 06, 2021

The history of machine learning in neurosurgery spans three decades and continues to develop at a rapid pace. The earliest applications of machine learning within neurosurgery were first published in ...

Explainable Artificial Intelligence for Human-Machine Interaction in Brain Tumor Localization.

Nov 29, 2021

Primary malignancies in adult brains are globally fatal. Computer vision, especially recent developments in artificial intelligence (AI), have created opportunities to automatically characterize and d...

Multifunctional Nanopolymers for Blood-Brain Barrier Delivery and Inhibition of Glioblastoma Growth through EGFR/EGFRvIII, c-Myc, and PD-1.

Nov 29, 2021

Glioblastoma (GBM) is the most prevalent primary brain cancer in the pediatric and adult population. It is known as an untreatable tumor in urgent need of new therapeutic approaches. The objective of ...

Direct oral anticoagulants or low-molecular-weight heparins for venous thromboembolism in patients with brain tumors.

Nov 22, 2021

Patients with central nervous system malignancies have limited representation in studies evaluating DOACs for VTE treatment. This study evaluated the safety and efficacy of DOACs in comparison with LM...

Relax and focus on brain tumor segmentation.

Nov 22, 2021

In this paper, we present a Deep Convolutional Neural Networks (CNNs) for fully automatic brain tumor segmentation for both high- and low-grade gliomas in MRI images. Unlike normal tissues or organs t...

Core-shell lipoplexes inducing active macropinocytosis promote intranasal delivery of c-Myc siRNA for treatment of glioblastoma.

Nov 15, 2021

Glioblastoma is the most common and aggressive primary brain tumor, whose malignancy is closely correlated with elevated proto-oncogene c-myc. Intranasal administration emerges as a potential approach...

3D Interactive Segmentation with Semi-Implicit Representation and Active Learning.

Nov 15, 2021

Segmenting complex 3D geometry is a challenging task due to rich structural details and complex appearance variations of target object. Shape representation and foreground-background delineation are t...

Nuclear FABP7 regulates cell proliferation of wild-type IDH1 glioma through caveolae formation.

Nov 01, 2021

Isocitrate dehydrogenase 1 (IDH1) is a key enzyme in cellular metabolism. IDH1 mutation (IDH1mut) is the most important genetic alteration in lower-grade glioma, whereas glioblastoma (GB), the most co...

Glycemia and venous thromboembolism in patients with primary brain tumors - A speculative review.

Nov 01, 2021

Venous thromboembolism (VTE) is a significant public health issue causing severe morbidity and mortality. One of the most vulnerable populations for VTE development are cancer patients. And among them...

Demographic Analysis of Financial Hardships Faced by Brain Tumor Survivors.

Oct 25, 2021

Quantitative analysis of the financial hardship faced by patients with brain tumors is lacking. As such, the present study sought to conduct a longitudinal analysis of responses to the National Health...

Genotype-cancer association in patients with Fanconi anemia due to pathogenic variants in FANCD1 (BRCA2) or FANCN (PALB2).

Oct 25, 2021

Fanconi anemia (FA) is the most common inherited bone marrow failure syndrome and a cancer predisposition disorder. Cancers in FA include acute leukemia and solid tumors; the most frequent solid tumor...

Headlight and loupe-based fluorescein detection system in brain tumor surgery; a firstin-human experience.

Oct 18, 2021

Fluorescein is an agent that accumulates in areas of blood-brain barrier breakdown and is commonly used in neurosurgical oncology to assist with lesion localization and visualizing the extent of resec...

Artificial Intelligence Applications in Pediatric Brain Tumor Imaging: A Systematic Review.

Oct 18, 2021

Artificial intelligence (AI) has facilitated the analysis of medical imaging given increased computational capacity and medical data availability in recent years. Although many applications for AI in ...

Gliomas in children and adolescents: investigation of molecular alterations with a potential prognostic and therapeutic impact.

Oct 11, 2021

Gliomas represent the most frequent central nervous system (CNS) tumors in children and adolescents. However, therapeutic strategies for these patients, based on tumor molecular profile, are still lim...

Assessment of cytotoxic effects of new derivatives of pyrazino[1,2-a] benzimidazole on isolated human glioblastoma cells and mitochondria.

Oct 11, 2021

Glioblastoma multiforme (GBM) is a highly devastating malignant brain tumor with poor pharmacotherapy. Based on COX-2 inhibitory effects in preventing cancer progression, new pyrazino[1,2-a]benzimidaz...

Physical activity levels, exercise preferences, and exercise barriers in Korean children and adolescents after cancer treatment.

Oct 04, 2021

The purpose of the current study was to explore physical activity (PA) levels, exercise preferences, and perceived barriers to PA in childhood cancer survivors.This cross-sectional study surveyed 120 ...

Clinical phenotypes and prognostic features of embryonal tumours with multi-layered rosettes: a Rare Brain Tumor Registry study.

Oct 04, 2021

Embryonal tumours with multi-layered rosettes (ETMRs) are a newly recognised, rare paediatric brain tumour with alterations of the C19MC microRNA locus. Due to varied diagnostic practices and scarce c...

Performance Improvement in Brain Tumor Detection in MRI Images Using a Combination of Evolutionary Algorithms and Active Contour Method.

Sep 27, 2021

The process of treating brain cancer depends on the experience and knowledge of the physician, which may be associated with eye errors or may vary from person to person. For this reason, it is importa...

Brain Tumor Detection Using Machine Learning and Deep Learning: A Review.

Sep 27, 2021

According to the international agency for research on cancer (IARC), the mortality rate due to brain tumors is 76%. It is required to detect the brain tumors as early as possible and to provide the pa...

Bicentric validation of the navigated transcranial magnetic stimulation motor risk stratification model.

Sep 20, 2021

The authors sought to validate the navigated transcranial magnetic stimulation (nTMS)-based risk stratification model. The postoperative motor outcome in glioma surgery may be preoperatively predicted...