Hepatitis B virus (HBV) infection is a worldwide distributing viral disease. Hepatitis due to HBV reactivation may progress to chronic illness and associated with increased risk of hepatic failure and hepatocellular cancer....
Cutaneous T-cell Lymphoma’s (CTCL) are a rare, heterogenous group of T-cell lymphomas that primarily manifest in the skin. Mycosis fungoides (MF) and Sézary syndrome (SS) are considered the claswsic types of CTCL. The...
Mantle cell lymphoma (MCL) is usually resistant to the current standard-of-care regimens and also to novel agents such as the proteasome inhibitor bortezomib. A better prognosis of leukemic variants of MCL suggests that MCL...
Sézary syndrome (SS) is an aggressive leukemic form of Cutaneous T-cell Lymphoma with neoplastic CD4+ T cells present in skin, lymph nodes, and blood. Despite advances in therapy, prognosis remains poor with a 5-year overall...
Macroscopic thromboembolic disease has been associated with canine neoplasia, whereas prevalence studies of concurrent microthrombi and tumor-cell emboli are lacking. This retrospective study investigated microthrombi and tumor...
Secondary central nervous system (CNS) lymphoma is a rare and often fatal complication of non-Hodgkin lymphoma (NHL). Treatment options include radiation therapy, high-dose systemic chemotherapy, intrathecal chemotherapy, and...
B-prolymphocytic leukemia (B-PLL) is included as a distinct entity in the current World Health Organization classification of hematolymphoid neoplasms. However, the diagnosis of B-PLL has presented several challenges since its...
This report presents an extremely rare case of synchronous gastric cancer and primary adrenal diffuse large B-cell lymphoma (DLBCL). An 82-year-old man underwent computed tomography, which revealed a heterogeneous appearing and...
Genetic studies have revealed a critical role of the distal-less homeobox gene 5 () in the pathogenesis of ovarian cancer, lung cancer, and T-cell lymphoma; however, the role and underlying mechanisms of in oral squamous cell...
Human immunodeficiency virus type 1 (HIV-1) matrix protein p17 variants (vp17s) derived from non-Hodgkin lymphoma (NHL) tissues of HIV-1-seropositive (HIV) patients promote B cell growth by activating the Akt signaling pathway....
Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase (RTK) that is mutated in approximately 10% of pediatric neuroblastoma (NB). To shed light on ALK-driven signaling processes, we employed BioID-based in vivo...
Mycosis fungoides with large cell transformation (MF-LCT) is associated with an aggressive clinical course yet data comparing treatment outcomes in MF-LCT are sparse.To compare treatment outcomes and to determine disease...
