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Dry Eye

Corneal Sensitivity and Patient-Reported Dry Eye Symptoms in a Prospective Randomized Contralateral-Eye Trial Comparing LASIK and SMILE.

May 23, 2022

To prospectively compare corneal sensation and patient-reported symptoms of dry eye in individuals undergoing laser-assisted in situ keratomileusis (LASIK) and small incision lenticule extraction (SMI...

Interventions for the management of computer vision syndrome: a systematic review and meta-analysis.

May 23, 2022

To evaluate the efficacy and safety of interventions for treating eye strain related to computer use relative to placebo or no treatment.Computer use is pervasive and often associated with eye strain,...

Current trends in pharmaceutical treatment of Dry Eye Disease: A review.

May 16, 2022

Dry eye disease (DED), keratoconjunctivitis sicca or dysfunctional tear syndrome, is the most prevalent ophthalmic disease which affects a substantial segment of people worldwide with increasing frequ...

The effect of time on grading corneal fluorescein and conjunctival lissamine green staining.

May 16, 2022

To explore the effect of time on grading corneal fluorescein and conjunctival lissamine green staining in dry eye disease (DED).Photographs of 68 subjects with non-Sjogren's DED (nSS DED) and 32 with ...

Management Strategies for Evaporative Dry Eye Disease and Future Perspective.

May 09, 2022

Dry eye disease (DED) is a common disorder that remains challenging from a clinical perspective. Unstable or deficient tear film is a major factor contributing to DED and the inability to resolve the ...

Optimization of IL-1RA structure to achieve a smaller protein with a higher affinity to its receptor.

May 09, 2022

Interleukine-1 family cytokines are key orchestrators of innate and adaptive immunity. In particular, up-regulation of IL-1R1 via its agonistic ligands consisting of IL-1β and IL-1α is implicated in...

Effects of systemic anti-androgen drugs on the ocular surface.

May 02, 2022

To investigate the effect of systemic anti-androgen drugs on tear function tests and the ocular surface.Sixty-four male subjects were included in this study. Subjects who were on anti-androgen treatme...

Role of neuroticism and perceived stress on quality of life among patients with dry eye disease.

May 02, 2022

This hospital-based, cross-sectional observational study aimed to examine whether neuroticism has an impact on stress that is related to dry eye disease (DED) and quality of life (QOL). One hundred pa...

Viscoelastic properties of the human tear film.

Apr 25, 2022

When considering eye blinking from a tribological perspective, tear viscosity is expected to play a fundamental role. The application of rheological techniques to describe the tear film dates back to ...

Prevalence and risk factors for dry eye disease: the Sao Paulo dry eye study.

Apr 18, 2022

To estimate the prevalence and risk factors of dry eye disease symptoms and clinical diagnoses in Sao Paulo city, state of Sao Paulo, Brazil.A total of 582 participants over 18 years old, living in th...

Preoperative dry eyes disease in cataract patients with deficient tear break up time: evaluation of OSDI questionnaire, its subcategories and Keratograph 5M device results.

Apr 11, 2022

To evaluate preoperatively dry eye disease (DED) in patients with pathological Tear Break Up Time (TBUT), utilising subjective Ocular Surface Disease Index (OSDI) with its subcategories and objective ...

Therapeutic Effects of Topical Application of Polysaccharide in a Murine Model of Dry Eye.

Apr 04, 2022

To evaluate the safety and efficacy of polysaccharide (LBP) eye drops in a murine model of dry eye disease (DED).Six- to eight-week-old female C57BL/6 mice were subjected to a combination of desiccat...

Intense pulsed light-based treatment for the improvement of symptoms in glaucoma patients treated with hypotensive eye drops.

Apr 04, 2022

Ocular surface disease in glaucoma patients is a significant ocular co-morbidity that can affect 40% to 59% of these patients worldwide. The current study was aimed at evaluating the potential clinic...

THE QUADRANGULAR SPACE, ENDONASAL ACCESS TO MECKEL'S CAVE: TECHNICAL CONSIDERATIONS AND CLINICAL SERIES.

Mar 28, 2022

An anteromedial corridor via an expanded endoscopic endonasal approach to Meckel's Cave (MC) was described over a decade ago. However, few clinical series or endoscopic endonasal technical contributio...

Altered regional brain white matter in dry eye patients: a brain imaging study.

Mar 28, 2022

This study aimed to investigate the regional changes of brain white matter (WM) in DE patients using diffusion tensor imaging (DTI) and neurite orientation dispersion and density imaging (NODDI). A to...

Dry Eye Symptom Severity and Visual Field Reliability Metrics.

Mar 21, 2022

Tracking failure frequency increases with dry eye symptom severity and in the left eye.Symptoms of dry eye disease are commonly encountered in glaucoma patients and can be exacerbated by topical glauc...

Post photorefractive keratectomy (PRK) infectious keratitis; six-year experience of a tertiary eye hospital.

Mar 14, 2022

As an essential development in the new century, surface ablation procedures have attracted increasing attention. There exists a concern regarding the risk of infectious keratitis. Hence, we aimed to i...

Analysis of Globular Cells in Corneal Nerve Vortex.

Mar 14, 2022

Less was known about globular cells which were a type of dendritic cells (DCs) in cornea. We aimed to investigate the morphological and distribution characteristics of globular cells in corneal vortex...

Necroptosis Contributes to Airborne Particulate Matter-Induced Ocular Surface Injury.

Mar 07, 2022

In this study, we explored the role of necroptosis in the pathogenesis of ocular surface injury caused by airborne particulate matter (PM). Human corneal epithelial (HCE) cells and mouse ocular surfac...

Visual loss and optic neuropathy in a patient with Klinefelter's syndrome, open-angle glaucoma, vitamin B (cobalamin) and folate deficiency.

Feb 28, 2022

A 54-year-old man with Klinefelter's syndrome presented to the neuro-ophthalmology clinic with progressive painless visual blurring in the right eye over 2 years. He was receiving intramuscular testos...