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Glaucoma

Prediction of visual field defects from macular optical coherence tomography in glaucoma using cluster analysis.

May 23, 2022

To assess the accuracy of cluster analysis-based models in predicting visual field (VF) defects from macular ganglion cell-inner plexiform layer (GCIPL) measurements in glaucomatous and healthy cohort...

Gaze tracker parameters have little association with visual field metrics of intrasession frontloaded SITA-Faster 24-2 visual field results.

May 23, 2022

To determine the usefulness of Humphrey Field Analyser (HFA) SITA-Faster 24-2 gaze tracker outputs on interpreting intra-visit visual field (VF) result pairs.Analysis of 1380 right-left eye pairs and ...

TMCO1 expression promotes cell proliferation and induces epithelial-mesenchymal transformation in human gliomas.

May 16, 2022

Transmembrane and coiled-coil domains 1 (TMCO1) is a recently discovered transmembrane protein of endoplasmic reticulum (ER), which plays a critical role in maintaining calcium homeostasis. TMCO1 dysf...

Ultrasound biomicroscopy of the equine iridocorneal angle.

May 16, 2022

The iridocorneal angle (ICA) is the major pathway of aqueous humor outflow from the anterior chamber of the eye. Ultrasound biomicroscopy (UBM) has been utilized to characterize the morphology of this...

Elevated TGFβ signaling contributes to ocular anterior segment dysgenesis in Col4a1 mutant mice.

May 09, 2022

Ocular anterior segment dysgenesis (ASD) refers to a collection of developmental disorders affecting the anterior structures of the eye. Although a number of genes have been implicated in the etiology...

White and non-White Australian mental health care practitioners' desirable responding, cultural competence, and racial/ethnic attitudes.

May 09, 2022

Racial, ethnic, religious, and cultural diversity in Australia is rapidly increasing. Although Indigenous Australians account for only approximately 3.5% of the country's population, over 50% of Austr...

Generation of 3D retinal tissue from human pluripotent stem cells using a directed small molecule-based serum-free microwell platform.

Apr 25, 2022

Retinal degenerative diseases are a leading cause of blindness worldwide with debilitating life-long consequences for the affected individuals. Cell therapy is considered a potential future clinical i...

Novel and investigational therapies for wet and dry age-related macular degeneration.

Apr 25, 2022

Age-related macular degeneration (AMD) is a macular degenerative eye disease, the major cause of irreversible loss of central vision. In this review, we highlight current progress and future perspecti...

Ground reaction forces during stair ascending and descending in congenitally blind and sighted individuals.

Apr 18, 2022

Stair ascending and descending are common in daily life activities which are challenging for blind individuals. Visual information plays an important role in controlling an individual's movements. How...

Patient Personality and Illness Perceptions in Relation to Follow-Up Appointment Adherence in Neuro-Ophthalmology.

Apr 18, 2022

Improving patient attendance at medical follow-up visits may have a notable impact on disease and overall health outcomes. Understanding factors contributing to poor attendance is important for identi...

The Peter Watson Memorial Lecture "Vision for the World".

Apr 11, 2022

In the 1990s attention was drawn to the huge global problem of blindness and vision loss; most of which was unnecessary, being preventable or treatable. This led to the global initiative, Vision 2020....

Anatomical Evidence for the Neural Connection from the Emotional Brain to Autonomic Innervation in the Anterior Chamber Structures of the Eye.

Apr 04, 2022

Previous studies have shown that the autonomic nervous system (ANS), which can be affected by emotions, is important in the occurrence or progression of glaucoma. The autonomic innervation distributed...

Tail-approach based design and synthesis of Arylthiazolylhydrazono-1,2,3-triazoles incorporating sulfanilamide and metanilamide as human carbonic anhydrase I, II, IV and IX inhibitors.

Apr 04, 2022

A library of twenty-two arylthiazolylhydrazono-1,2,3-triazoles incorporating sulfanilamide and metanilamide moieties have been synthesized by utilizing tail-approach and characterized by their IR, H N...

Burden and depression among informal caregivers of visually impaired patients in Mexico.

Mar 28, 2022

The needs of informal caregivers who provide care to family relatives with visual impairment are often neglected, resulting in burden and depression.To determine the degree of burden and the prevalenc...

Retinal detachment after cataract surgery: a population-based study.

Mar 28, 2022

To analyse the risk of rhegmatogenous retinal detachment (RRD) after cataract surgery, and to identify possible risk factors.Observational cohort study of patients undergoing cataract surgery in Regio...

A deep learning approach for detection of shallow anterior chamber depth based on the hidden features of fundus photographs.

Mar 21, 2022

Patients with angle-closure glaucoma (ACG) are asymptomatic until they experience a painful attack. Shallow anterior chamber depth (ACD) is considered a significant risk factor for ACG. We propose a d...

Evaluation of UNC OCT Index for Diagnosis of Early Glaucoma.

Mar 14, 2022

To evaluate the diagnostic performance of the University of North Carolina Optical Coherence Tomography (UNC OCT) Index based on Cirrus high-definition optical coherence tomography to discriminate ear...

Ischemic ocular manifestations of giant cell arteritis: A Canadian case series.

Mar 14, 2022

Diagnosing giant cell arteritis (GCA) can be challenging due to the variable clinical presentation and lack of systemic symptoms in approximately 20% of cases, which are termed occult GCA. GCA affects...

The Three-Dimensional Structural Configuration of the Central Retinal Vessel Trunk and Branches as a Glaucoma Biomarker.

Mar 07, 2022

To assess whether the three-dimensional (3D) structural configuration of the central retinal vessel trunk and its branches (CRVT&B) could be used as a diagnostic marker for glaucoma.Retrospective,...

Drug induced cicatrizing conjunctivitis: A case series with review of etiopathogenesis, diagnosis and management.

Mar 07, 2022

Drug induced cicatrizing conjunctivitis (DICC) is defined as a disease in which conjunctival cicatrization develops as a response to the chronic use of inciting topical and, rarely, systemic medicatio...