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Orthopedics General

Icariin stimulates osteogenesis and suppresses adipogenesis of human bone mesenchymal stem cells via miR-23a-mediated activation of the Wnt/β-catenin signaling pathway.

Mar 22, 2021

Icariin (ICA) is a bioactive compound isolated from epimedium-derived flavonoids that modulates bone mesenchymal stem cell osteogenesis and adipogenesis. However, its precise mechanism in this process...

Electrosprayed calcium silicate nanoparticle-coated titanium implant with improved antibacterial activity and osteogenesis.

Mar 22, 2021

To ensure clinical success, the implant and the surrounding bone tissue must not only be integrated, but also must not be suspected of infection. In this work, an antibacterial and bioactive nanostruc...

Brucellosis in Transplant Recipients: A Systematic Review.

Mar 22, 2021

Brucellosis, a bacterial disease caused by Brucella species. The purpose of this study was to evaluate brucellosis in all types of transplant patients.All the cases of brucellosis in transplant patien...

Trabecular bone score in women with differentiated thyroid cancer on long-term TSH-suppressive therapy.

Mar 18, 2021

Thyrotropin stimulating hormone (TSH) suppression in patients with differentiated thyroid cancer (DTC) aims to decrease the growth and proliferation of thyroid cancer cells. However, the effect of TSH...

Spine and pelvis coordination variability in rowers with and without chronic low back pain during rowing.

Mar 18, 2021

The aim of this study was to compare the spine-pelvis coordination and coordination variability (CV) during rowing in elite rowers with and without chronic low back pain (CLBP). Fourteen professional ...

Postcranial Skeletal Pneumaticity in Cuculidae.

Mar 18, 2021

Postcranial skeletal pneumaticity (i.e., epithelial-lined, air-filled bones) is a condition unique to birds among extant tetrapods. Previous research reveals extensive variation in the expression of t...

The Role of 3D Reconstruction of the Skull in Patients with Suspected Shunt Malfunction.

Mar 18, 2021

Mechanical shunt malfunction may lead to significant morbidity and mortality. Shunt series assessments help evaluate shunt integrity; however, they are of limited value in the area of the skull due to...

Management of low back pain: Treatment provision within private practice in the UK in the context of clinical guidelines.

Mar 15, 2021

To summarise the combination of treatments private UK-based physiotherapists use with patients who have low back pain (LBP) and the extent to which the treatments used are consistent with clinical gui...

Does the management of osteofibrous dysplasia of the tibia and fibula in children should be tailored to the extent and location of the lesion? A case control study investigating different surgical options.

Mar 15, 2021

Osteofibrous dysplasia (OFD) is a rare non neoplastic, self-limited intracortical fibro-osseous lesion that most commonly affects the diaphysis of the tibia and fibula of children, the best treatment ...

Injury patterns and demographics due to legal intervention seen in US emergency departments.

Mar 15, 2021

Injury and deaths inflicted by law enforcement are a topic of significant discussion in the US. The purpose of this study was to analyze injuries due to law enforcement activity that presented to emer...

Lead contamination in tissues of large avian scavengers in south-central Europe.

Mar 15, 2021

Lead poisoning from spent ammunition is known to affect many avian species. Birds of prey ingest lead when feeding on game shot with lead gunshot or bullets. Raptors with scavenging habits are particu...

Prevalence of vitamin D deficiency in an inpatient population in the Swiss Canton of Basel-Country.

Mar 15, 2021

Vitamin D deficiency remains very common in the general population. Adding to the importance of this issue is the discovery that vitamin D plays a role in many other tissues apart from the bone, inclu...

Association between periodontitis treatment outcomes and peri-implantitis: a long-term retrospective cohort study.

Mar 15, 2021

Retrospectively evaluate the association of periodontal treatment outcomes and the prevalence of peri-implant diseases around tissue-level implants.Eighty-six patients with 260 tissue-level implants (...

Steep posterior lateral tibial slope, bone contusion on lateral compartments and combined medial collateral ligament injury are associated with the increased risk of lateral meniscal tear.

Mar 11, 2021

To determine the risk factors for lateral meniscus and root tears in patients with acute anterior cruciate ligament (ACL) injuries.A total of 226 patients undergoing acute ACL reconstruction were incl...

Anterior odontoid screw fixation extrusion as reason for oesophagus perforation.

Mar 11, 2021

Type II odontoid fractures are mostly encountered in the elderly. Due to a high risk of non-union fractures in the case of conservative treatment, surgical fixation is widely recommended. Anterior odo...

Fabrication of nanocomposite/nanofibrous functionally graded biomimetic scaffolds for osteochondral tissue regeneration.

Mar 11, 2021

One of the main challenges in treating osteochondral lesions via tissue engineering approach is providing scaffolds with unique characteristics to mimic the complexity. It has led to application of he...

Influence of the dental implant number and load direction on stress distribution in a 3-unit implant-supported fixed dental prosthesis.

Mar 11, 2021

The choice between 2 or 3 implants to support a 3-unit implant-supported fixed dental prosthesis (FDP) still generates doubt in clinical practice.The aim of this study was to evaluate stress distribut...

A case of ankle osteoarthritis associated with lateral premalleolar bursitis caused by chronic ankle instability.

Mar 08, 2021

Lateral premalleolar bursitis develops on the dorsolateral aspect of the foot anterior to the lateral malleolus, distinct from lateral malleolar bursitis located just around the lateral malleolus.A 71...

Biomechanical evaluation of glass fiber/polypropylene composite bone fracture fixation plates: Experimental and numerical analysis.

Mar 08, 2021

Little is known about the impact behavior of composite fixation plate used in the fracture healing of long bones diaphysis. Hence, this study examined polypropylene composite fixation plates using dif...

Bone-cartilage mismatch in the medial tibial plateau: A MRI study.

Mar 08, 2021

Bone-cartilage mismatch is a variation in which the surface curvature of the articular cartilage is incongruent with the curvature of the underlying subchondral bone. The purpose of this study is to i...

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