Jul 07, 2025

The cortical thickness index (CTI) is a radiological measure and correlates with diminishing local bone quality in the proximal femur. The objective of this study was to assess the association between...

Jul 07, 2025

Intervertebral disc degeneration (IDD) is a leading cause of discogenic lower back pain, yet the crosstalk between macrophage polarization and nucleus pulposus (NP) cell senescence in IDD progression ...

Jul 07, 2025

Diabetic kidney disease (DKD) imposes a heavy medical burden worldwide due to the lack of effective treatment. High levels of mtROS and mitochondrial damage in the renal tubules are the initiating and...

Jun 16, 2025

Bleeding represents a critical challenge across diverse medical scenarios, underscoring the urgent need for the development of advanced hemostatic materials. This review focuses on gelatin-based hemos...

Jun 09, 2025

In acute myeloid leukemia (AML), disease relapse is often observed because of therapy-resistant leukemic stem cells that re-initiate the disease. Leukemic stem cells can tightly associate with mesench...

Jun 09, 2025

To investigate the utilization of cone beam computed tomography (CBCT) in paediatric dentistry, focusing on the indications, referring departments, age distribution, oral regions examined, and fields ...

May 26, 2025

Aiming at the problem that the roof of the soft-hard interbedded coal seam is prone to delamination and caving without warning during coal mining, taking the No. 2201 working face of a certain mine as...

May 12, 2025

Obesity is associated with skeletal deterioration and increased fracture risk, but the underlying mechanism is unclear. Herein, it is shown that obese gut microbiota promotes skeletal deterioration by...

May 05, 2025

Hip fractures are a significant public health concern due to increasing numbers, high mortality and negative impact on health-related quality of life (HRQoL). Socioeconomic position (SEP) affects vari...

Apr 28, 2025

The Fracture Risk Assessment Tool (FRAX), widely used for predicting the 10-year likelihood of hip fractures, does not incorporate factors like prior falls and sociodemographic characteristics, notabl...

Apr 28, 2025

Cytomegalovirus (CMV), a beta-herpesvirus capable of maintaining lifelong latency, presents a substantial risk to transplant recipients, resulting in significant morbidity and mortality among both hem...

Apr 21, 2025

To evaluate the ability of the liquid-injectable OdneFill sealer to stay within the boundaries of prepared root canals of posterior teeth using a cadaveric model.Eight maxillary bone blocks containing...

Apr 14, 2025

Juvenile Paget disease (JPD) is a very rare disease, mainly caused by biallelic inactivating mutations in the TNFRSF11B gene that encodes osteoprotegerin. Owing to its rarity, the treatment of JPD is ...

Apr 14, 2025

In clear aligner treatment (CAT), closure of the premolar space is achieved by reducing aligner length. Posterior anchorage preparation is effective in preserving molar angulation; however, the result...

Apr 14, 2025

Scoliosis considerably affects adolescents' physical well-being and quality of life. Current research offers scant data concerning the correlation between abnormal posture, screen time, physical activ...

Mar 17, 2025

Intervertebral disc degeneration (IVDD) is a primary contributor to low back pain, posing significant social and economic burdens. Increasing evidence shows that obesity contributes to IVDD, yet the u...

Mar 17, 2025

Current processing techniques for harvesting DNA from osseous elements are destructive, and success rates vary widely. When skeletal elements are homogenized into a fine powder, endogenous DNA may be ...

Feb 17, 2025

To evaluate the effectiveness of an evidence-based pre-, peri- and postoperative rehabilitation pathway (i.e. the REACT rehabilitation pathway) on disability in patients undergoing lumbar fusion surge...

Feb 17, 2025

Sarcopenia, characterized by age-related loss of muscle mass and function, significantly impacts the quality of life of older adults. This condition is prevalent among elderly patients with hip fractu...

Feb 17, 2025

MicroRNAs (miRNAs) play a crucial role in cell differentiation through epigenetic regulation of gene expression. In human dental pulp cells, we have identified miRNA-27a being upregulated under inflam...