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Pain General

Acute Treatments for Episodic Migraine in Adults: A Systematic Review and Meta-analysis.

Jun 17, 2021

Migraine is common and can be associated with significant morbidity, and several treatment options exist for acute therapy.To evaluate the benefits and harms associated with acute treatments for episo...

Effects of Intravenous Eptinezumab vs Placebo on Headache Pain and Most Bothersome Symptom When Initiated During a Migraine Attack: A Randomized Clinical Trial.

Jun 17, 2021

Intravenous eptinezumab, an anti-calcitonin gene-related peptide antibody, is approved for migraine prevention in adults. It has established onset of preventive efficacy on day 1 after infusion.To eva...

Gait kinematic alterations in subjects with adult spinal deformity and their radiological determinants.

Jun 14, 2021

Adults with spinal deformity (ASD) are known to have postural malalignment affecting their quality of life. Classical evaluation and follow-up are usually based on full-body static radiographs and hea...

Leojaponin inhibits NLRP3 inflammasome activation through restoration of autophagy via upregulating RAPTOR phosphorylation.

Jun 14, 2021

Duan Teng Yimu decoction is a Chinese herbal medicine compound with proven therapeutic effects on inflammasome-related diseases, such as rheumatoid arthritis. This decoction consists of three Chinese ...

Protein kinase C δ as a neuronal mechanism for headache in a chronic intermittent nitroglycerin model of migraine in mice.

Jun 14, 2021

Migraine is one of the most common neurological disorders characterized by recurrent attacks of typically throbbing and unilateral headaches, affecting up to 20 % of the population worldwide. Despite ...

Pain, cannabis use, and physical and mental health indicators among veterans and non-veterans: results from National Epidemiologic Survey on Alcohol and Related Conditions-III.

Jun 14, 2021

Chronic pain is associated with mental and physical health difficulties and is prevalent among veterans. Cannabis has been put forth as a treatment for chronic pain, and changes in laws, attitudes, an...

Effect of intraoperative methadone vs other opioids on postoperative outcomes: a meta-analysis of randomized controlled studies.

Jun 14, 2021

Recent randomized controlled trials comparing the efficacy between intraoperative methadone and other opioids on postoperative outcomes have been limited by their small sample sizes and conflicting re...

Fatal opioid overdoses in the U.S. declined more than reported between 2017 and 2018.

Jun 10, 2021

: In U.S. death records, many drug overdoses do not have classified drug involvement, which challenges surveillance of opioid overdoses across time and space.: To estimate the 2017-2018 change in opio...

Differences and similarities between emergency department syndromic surveillance and hospital discharge data for nonfatal drug overdose.

Jun 10, 2021

Emergency department (ED) syndromic surveillance and hospital discharge data have been used to detect and monitor nonfatal drug overdose, yet few studies have assessed the differences and similarities...

Prescription opioid policies and associations with opioid overdose and related adverse effects.

Jun 10, 2021

United States (US) policies to mitigate the opioid epidemic focus on reducing access to prescription opioids to prevent overdoses. We examined the impact of state policies in Vermont (July 2017) and M...

Internet addiction, headache, and insomnia in university students: a cross-sectional study.

Jun 10, 2021

There is controversy about whether there is an association between headache and internet addiction. Therefore, the objective was to assess whether there is an association between the headache, insomni...

Validity and reliability of the self-administered Visual Aura Rating Scale questionnaire for migraine with aura diagnosis: A prospective clinic-based study.

Jun 10, 2021

To assess the validity and reliability of the self-administered Visual Aura Rating Scale (VARS) questionnaire using a hospital-based sample in a cross-sectional setting.Visual aura is the most common ...

Validity and reliability of the Turkish version of the shoulder rating questionnaire in patients with shoulder pain.

Jun 10, 2021

The aim of this study was to translate the Shoulder Rating Questionnaire (SRQ-T) into Turkish and to determine the validity and reliability of the translated version in patients shoulder pain.The Turk...

Pulsed electromagnetic field (PEMF) as an adjunct therapy for pain management in interstitial cystitis/bladder pain syndrome.

Jun 10, 2021

Patients with interstitial cystitis/bladder pain syndrome (IC/BPS) often experience chronic pelvic and even systemic pain that can be difficult to clinically manage. Pulsed electromagnetic field (PEMF...

3D magnetic resonance spectroscopic imaging reveals links between brain metabolites and multidimensional pain features in fibromyalgia.

Jun 10, 2021

Fibromyalgia is a centralized multidimensional chronic pain syndrome, but its pathophysiology is not fully understood.We applied 3D magnetic resonance spectroscopic imaging (MRSI), covering multiple c...

Three-Dimensional Sonographic Evaluation of the Position of the Fetal Conus Medullaris at First Trimester.

Jun 10, 2021

The objective of this study was to assess the position of the conus medullaris (CM) at the first trimester 3D ultrasound in a cohort of structurally normal fetuses.This was a multicenter prospective s...

Bicortical Short C2 Pars Screw Fixation for High-Riding Vertebral Artery Provided Sufficient Biomechanical Stability: A Finite Element Study.

Jun 10, 2021

Finite element analysis.To determine and compare the biomechanical stability of the bicortical short C2 pars screw fixation for high-riding vertebral artery (HRVA) with the C2 pedicle screw and C2 tra...

Characterizing Health-Related Quality of Life by Ambulatory Status in Patients With Spinal Metastases.

Jun 10, 2021

Retrospective review of prospective longitudinal data.To determine health-related quality of life (HRQL) utilities associated with specific ambulatory states in patients with spinal metastases: indepe...

Association of Granuloma Annulare With Type 2 Diabetes, Hyperlipidemia, Autoimmune Disorders, and Hematologic Malignant Neoplasms.

Jun 10, 2021

Although granuloma annulare (GA) has been associated with several other conditions, these studies have been limited by single-center designs and small sample sizes.To evaluate whether there is an asso...

Clinical characteristics of interstitial lung diseases positive to different anti-synthetase antibodies.

Jun 10, 2021

To analyze the clinical, serological, and imaging characteristics of patients with interstitial lung diseases (ILD) positive to different anti-aminoacyl-tRNA synthetase (anti-ARS) antibodies.The clini...

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