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Pain General

Cognitive therapy, mindfulness-based stress reduction, and behavior therapy for the treatment of chronic pain: a single-blind randomized controlled trial.

Jun 03, 2021

Trials of Cognitive Therapy (CT), Mindfulness-Based Stress Reduction (MBSR), and Behavior Therapy (BT) suggest that all three treatments produce reductions in pain and improvements in physical functio...

Pain by mistake: investigating a link between error-related negativity and pain avoidance behavior.

Jun 03, 2021

Pain can be considered as a signal of "bodily error": Errors put organisms at danger and activate behavioral defensive systems. If the error is of physical nature, pain is the warning signal that moti...

Investigating how combined multifidus injury and facet joint compression influence changes in surrounding muscles and facet degeneration in the rat.

May 31, 2021

To examine whether unilateral multifidus damage could promote degeneration at the L5-6 facet joint (FJ) and compensatory changes in lumbo-pelvic muscles in rats.12 facet clamp, 12 facet sham and 7 con...

Rapid evidence and gap map of virtual care solutions across a stepped care continuum for youth with chronic pain and their families in response to the COVID-19 pandemic.

May 31, 2021

Poor access to pediatric chronic pain care is a longstanding concern. The COVID-19 pandemic has necessitated virtual care delivery at an unprecedented pace and scale. We conducted a scoping review to ...

Longitudinal study of early adaptation to the coronavirus disease pandemic among youth with chronic pain and their parents: effects of direct exposures and economic stress.

May 31, 2021

The novel coronavirus disease (COVID-19) has caused prolonged disruptions in daily life for many communities. Little is known about the impact of the COVID-19 pandemic on the health and well-being of ...

Pharmacist medication review: An integrated team approach to serve home-based primary care patients.

May 27, 2021

Comprehensive medication review is a patient-centered approach to optimize medication use and improve patient outcomes. This study outlines a pilot model of care in which a remote corporate-based clin...

Defining and Describing Treatment Heterogeneity in New-Onset Idiopathic Lower Back and Extremity Pain Through Reconstruction of Longitudinal Care Sequences.

May 27, 2021

Despite established guidelines, long-term management of surgically-treated low back pain (LBP) and lower extremity pain (LEP) remains heterogeneous. Understanding care heterogeneity could inform futur...

Improvements on a chemically contiguous hapten for a vaccine to address fentanyl-contaminated heroin.

May 27, 2021

Unintentional overdose deaths related to opioids and psychostimulants have increased in prevalence due to the adulteration of these drugs with fentanyl. Synergistic effects between illicit compounds a...

Predictors of Improvement in Pediatric Chronic Migraine: Results from the Cognitive-Behavioral Therapy and Amitriptyline Trial.

May 27, 2021

Explore predictors of improvement in headache days and migraine-related disability through a secondary analysis of the cognitive-behavioral therapy plus amitriptyline trial in children and adolescents...

Burden of migraine and unmet needs from the patients' perspective: a survey across 11 specialized headache clinics in Korea.

May 27, 2021

Migraine is a neurological, primary headache disorder affecting more than 1 billion people worldwide, with a multi-faceted burden that can significantly impact the everyday life of a patient, both dur...

InterMiG: international differences in the therapeutic approach to migraine patients in specialized headache centers.

May 27, 2021

There is currently a wide therapeutic arsenal for migraine patients, without a single first-line preventive drug and we choose the different available alternatives taking into account comorbidities, n...

Sarcopenia Is Associated With Increased Risks of Rotator Cuff Tendon Diseases Among Community-Dwelling Elders: A Cross-Sectional Quantitative Ultrasound Study.

May 27, 2021

Recently, the association between sarcopenia and various musculoskeletal disorders, such as lumbar spine stenosis and fibromyalgia, has been highlighted. However, the relationship between sarcopenia ...

Visit-to-visit blood pressure variability and regional cerebral perfusion decline in older adults.

May 27, 2021

Blood pressure variability (BPV) is linked to dementia risk, possibly through cerebral hypoperfusion. We investigated BPV over 1 year and concurrent regional cerebral perfusion decline in older adults...

Talking about post-injury sexual functioning: The views of people with spinal cord injuries-A qualitative interview study.

May 27, 2021

This study aimed to explore perceptions of people with spinal cord injuries regarding the information they received during their rehabilitation programme on post-injury sexual functioning.Spinal cord ...

Peritraumatic 17β-estradiol levels influence chronic posttraumatic pain outcomes.

May 27, 2021

Biologic factors that predict risk for and mediate the development of common outcomes of trauma exposure such as chronic posttraumatic pain (CPTP) are poorly understood. In the current study, we exami...

Central Sensitization Inventory in endometriosis.

May 27, 2021

A key clinical problem is identifying the endometriosis patient whose pain is complicated by central nervous system sensitization, where conventional gynecologic treatment (e.g. hormonal therapy or su...

Deficit of β-endorphin neurons in the hypothalamus and high expression of MOR in mesolimbic structures are related to high alcohol consumption in outbred rats.

May 24, 2021

Clinical studies have postulated that β-endorphin deficiency generates excessive alcohol consumption and, it has been shown that the reduction of β-endorphin neurons increases alcohol intake in anim...

Impact of COVID-19 on chronic migraine treated with erenumab: a case report.

May 24, 2021

Headache is a frequent symptom of the novel coronavirus 19 disease (COVID-19). To date, there are limited information on how COVID-19 affects migraine and its treatment.A 47-year-old patient, sufferin...

Patient experience of telemedicine for headache care during the COVID-19 pandemic: An American Migraine Foundation survey study.

May 24, 2021

We sought to investigate the patient experience of telemedicine for headache care during the coronavirus disease 2019 (COVID-19) pandemic.The use of telemedicine has rapidly expanded and evolved since...

The effect of COVID19 public health restrictions on the health of people with musculoskeletal conditions and symptoms: the CONTAIN study.

May 24, 2021

To quantify the change in quality of life, disease-specific indicators, health, and lifestyle before and during the COVID19 pandemic amongst people with musculoskeletal diagnoses and symptoms.We under...

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