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Pain General

Best Practices for Chiropractic Management of Patients with Chronic Musculoskeletal Pain: A Clinical Practice Guideline.

Aug 06, 2020

To develop an evidence-based clinical practice guideline (CPG) through a broad-based consensus process on best practices for chiropractic management of patients with chronic musculoskeletal (MSK) pai...

Where and how alpha-synuclein pathology spreads in Parkinson's disease.

Aug 06, 2020

In Parkinson's disease (PD), neuronal alpha-synuclein aggregates are distributed throughout the nervous system, including the brain, spinal cord, sympathetic ganglia, submandibular gland, enteric nerv...

Enhanced Recovery After Surgical Correction of Adolescent Idiopathic Scoliosis.

Aug 06, 2020

Few publications in the literature examine enhanced recovery after scoliosis surgery (ERAS) in children, despite significant scientific interest in adults. The objective of the current study was to de...

Prevalence of high-riding vertebral artery: a meta-analysis of the anatomical variant affecting choice of craniocervical fusion method and its outcome.

Aug 06, 2020

A high-riding vertebral artery (HRVA) is defined as C2 isthmus height ≤ 5 mm or/and internal height ≤ 2 mm measured 3 mm lateral to the border of the spinal canal. Its reported prevalence varies w...

Sustainable effects of 8-year intermittent spinal cord stimulation in a patient with thalamic post-stroke pain.

Aug 06, 2020

Central post-stroke pain (CPSP) is a central neuropathic pain syndrome secondary to a cerebrovascular accident. CPSP treatment usually begins with medication; however, this is associated with inadequa...

Community Attitudes Toward Opioid Use Disorder and Medication for Opioid Use Disorder in a Rural Appalachian County.

Aug 03, 2020

To evaluate community attitudes concerning opioid use disorder (OUD) and medication for opioid use disorder (MOUD) in a rural community, and to plan educational initiatives to reduce stigma surroundin...

Quadratus lumborum block for postoperative analgesia after cesarean delivery: A systematic review with meta-analysis and trial-sequential analysis.

Aug 03, 2020

The aim of this study was to investigate the analgesic efficacy of Quadratus lumborum block (QLB) versus controls, transversus abdominis plane (TAP) block and neuraxial morphine, or when added to neur...

Association between timing of kyphoplasty and opioid prescribing risk after vertebral fracture.

Aug 03, 2020

Approximately 550,000 Americans experience vertebral fracture annually, and most receive opioids to treat the resulting pain. Kyphoplasty of the fractured vertebra is a procedural alternative that may...

Iron Deposits in Periaqueductal Gray Matter Are Associated with Poor Response to OnabotulinumtoxinA in Chronic Migraine.

Aug 03, 2020

Previous studies have reported increased brain deposits of iron in patients with chronic migraine (CM). This study aims to determine the relation between iron deposits and outcome after treatment with...

The Ambiguous Role of Caffeine in Migraine Headache: From Trigger to Treatment.

Aug 03, 2020

Migraine is a chronic disorder, and caffeine has been linked with migraine for many years, on the one hand as a trigger, and on the other hand as a cure. As most of the population, including migraineu...

Characteristics of Acute Nystagmus in the Pediatric Emergency Department.

Aug 03, 2020

Acute nystagmus (AN) is an uncommon neurologic sign in children presenting to pediatric emergency departments. We described the epidemiology, clinical features, and underlying causes of AN in a large ...

The Valued Life Activities Scale (VLAs): linguistic validation, cultural adaptation and psychometric testing in people with rheumatic and musculoskeletal diseases in the UK.

Aug 03, 2020

The Valued Life Activities Scale (VLAs) measures difficulty in daily activities and social participation. With various versions involving a different number of items, we have linguistically and cultur...

Inhibition of acid ceramidase regulates MHC class II antigen presentation and suppression of autoimmune arthritis.

Aug 03, 2020

The bioactive sphingolipid ceramide affects immune responses although its effect on antigen (Ag) processing and delivery by HLA class II to CD4+T-cells remains unclear. Therefore, we examined the acti...

Effect of an Early Palliative Care Telehealth Intervention vs Usual Care on Patients With Heart Failure: The ENABLE CHF-PC Randomized Clinical Trial.

Aug 03, 2020

National guidelines recommend early palliative care for patients with advanced heart failure, which disproportionately affects rural and minority populations.To determine the effect of an early pallia...

DACC Resting State Functional Connectivity as a Predictor of Pain Symptoms Following Motor Vehicle Crash: A Preliminary Investigation.

Aug 03, 2020

There is significant heterogeneity in pain outcomes following motor vehicle crashes (MVCs), such that a sizeable portion of individuals develop symptoms of chronic pain months after injury while other...

The association between lower Hounsfield units of the upper instrumented vertebra and proximal junctional kyphosis in adult spinal deformity surgery with a minimum 2-year follow-up.

Aug 03, 2020

Patients undergoing long-segment fusions from the lower thoracic (LT) spine to the sacrum for adult spinal deformity (ASD) correction are at risk for proximal junctional kyphosis (PJK). One mechanism ...

Pain catastrophizing is associated with the Val66Met polymorphism of the brain-derived neurotrophic factor in fibromyalgia.

Aug 03, 2020

Fibromyalgia (FM) is a musculoskeletal chronic pain syndrome that impacts negatively patient's daily lives. Its pathogenesis is characterized by a complex relationship between biological and psychosoc...

Gabapentinoid Benefit and Risk Stratification: Mechanisms Over Myth.

Aug 03, 2020

Recent years have seen a dramatic escalation of off-label prescribing for gabapentin and pregabalin (gabapentinoids) owing in part to generic versions of each being released over the past two decades,...

Preoperative bone health assessment and optimization in spine surgery.

Aug 03, 2020

The purpose of this investigation was to characterize the bone health in preoperative spine surgery patients. This information will provide a framework to understand the needs and methods for providin...

Association of osteopenia and osteoporosis with higher rates of pseudarthrosis and revision surgery in adult patients undergoing single-level lumbar fusion.

Aug 03, 2020

Patients with osteopenia or osteoporosis who require surgery for symptomatic degenerative spondylolisthesis may have higher rates of postoperative pseudarthrosis and need for revision surgery than pat...

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