Vitamin D receptor (VDR) and NLRP3 inflammasome play critical roles in lupus nephritis (LN) pathogenesis.This study explored the therapeutic effect of VDR agonist on LN and its molecular mechanism to inhibit NLRP3...
Osteoarthritis (OA) is a prevailing chronic disease in Orthopedics that characterized with severely damaged cartilage and subchondral bone, thus leading to profound disorders of synovial joints. Platelet-rich plasma (PRP) has...
Several factors present at the time of posterior cruciate ligament reconstruction (PCLR) may cause the subsequent progression of articular cartilage lesions. This study aimed to evaluate postsurgical articular cartilage lesions...
“Patients with psoriasis are at an increased risk for cardiovascular disease and die several years...
There continues to be rapid advancement in the understanding of pathogenesis of immune mediated kidney disease. This progress has culminated into development of multiple therapeutic agents that have consistently improved renal...
Tubular basement membrane (TBM) deposits are very uncommon in non-lupus membranous nephropathy. We report a series of 5 patients with membranous nephropathy and extensive TBM deposits following allogeneic hematopoietic cell...
The objective of this meta-analysis was to review the diagnostic performance of anti-dsDNA testing, to determine whether test specificity meets the revised 2019 EULAR/ACR classification criteria for systemic lupus erythematosus...
Musculoskeletal pain is a risk factor for leaving the labour market temporarily and permanently. While the presence of multi-site pain increases the risk of disability pension, we lack detailed knowledge about pain intensity as...
Orthopedic conditions includes a range of condition varying from traumatic injuries, congenital anomalies, chronic back pain, arthritis, rheumatologic conditions, and other. Length of hospital stay is determined by a number of...
Recent studies indicate that Toll-like receptors (TLRs) and C-type lectin receptors (CLRs) can function as the signal of pattern recognition receptors, which play a pivotal role in the pathogenesis of the autoimmune disease....
Coronavirus disease 2019 (COVID-19) possesses a substantial challenge for rheumatologists and rheumatologic patients. They are concerned about the reciprocal interaction between connective tissue diseases, such as systemic lupus...
To explore the clinical and pathological features, therapy and prognosis of Castleman’s disease (CD) in the head and neck.We retrospectively analyzed the clinical and pathological data of 44 patients with head and neck CD...
