Medical devices (MD) in close skin-contact for prolonged time such as glucose monitoring(CGM) systems are a risk factor for contact allergy. There is an increase in patients using these. Correct diagnosis demands aimed correct testing. We report a new allergen in a continuous CGM system where the adhesive was changed. The allergy pattern of the patients diagnosed is reported due to the finding of polysensitization.
The three patients reported were patch tested with an MD series, own material and possible allergens found through analysis with gas chromatography-mass spectrometry comparing analysis from the CGM system prior and after change.
The patients were previously sensitized to isobornyl acrylate (IBOA), found in previously used devices and the present CGM. Apart from IBOA, the culprit allergen was found to be 2,2′-methylenebis(6-tert-butyl-4-methylphenol) monoacrylate.
Allergic contact dermatitis due to CGM systems and insulin pumps are difficult to investigate and require chemical analysis. Due to lack of information on substances used in the production and when changes with MDs are initiated, it is difficult to give advice to the patients, especially since they risk sensitization to several allergens. The use of MDs increase and thus the need for collaboration between producers, clinicians and patient organizations. This article is protected by copyright. All rights reserved.

This article is protected by copyright. All rights reserved.