The following is a summary of “Risk of hospitalization in a sample of COVID-19 patients with and without chronic obstructive pulmonary disease,” published in the January 2023 issue of Pulmonology by Myers, et al.
The effects of the coronavirus disease 2019 (COVID-19) may be harsh for patients with chronic obstructive pulmonary disease (COPD). Therefore, in individuals with and without COPD, the risk of COVID-19 hospitalization was compared by the researchers for a study.
The patients in the retrospective cohort analysis were≥40 years, SARS-CoV-2 positive, and members of Kaiser Permanente Northern California for ≥1 year prior to the diagnosis of COVID-19 (electronic health records and claims data). Sequentially adjusted logistic regression models were used to evaluate the risk of hospitalization associated with COVID-19 and were stratified by illness severity. Death or hospice referral following COVID-19 was a secondary result.
Around 697 (3.6%) of the 19,558 COVID-19 patients had COPD. Patients with COPD were older (median age: 69 vs. 53 years), had higher Elixhauser Comorbidity Index (5 vs. 0), and had more median baseline outpatient (8 vs. 4), emergency department (2 vs 1), and inpatient (2 vs 1) contacts than patients without COPD. The risks of being hospitalized with COPD were higher according to unadjusted analysis (odds ratio [OR]: 3.93; 95% CI: 3.40-4.60). After complete risk adjustment, there was no difference between patients with and without COPD in the chances of hospitalization (OR: 1.14, 95% CI: 0.93-1.40) or death/hospice referral (OR: 0.96, 95% CI: 0.72-1.27). Except for more significant risks of hospitalization in COPD patients needing supplementary oxygen compared to those without COPD (OR: 1.84, 95% CI: 1.02-3.33), primary/secondary outcomes did not differ by COPD severity.
In the COVID-19 patient sample, there were no changes in the likelihood of hospitalization or death/hospice referral based on whether the patient used supplemental oxygen.