G protein-coupled receptor GPR151 is involved in trigeminal neuropathic pain via the induction of Gβγ/ERK-mediated neuroinflammation in the trigeminal ganglion.
Trigeminal nerve injury-induced neuropathic pain is a debilitating chronic orofacial pain syndrome but lack of effective treatment. G protein-coupled receptors (GPCRs), especially orphan GPCRs (oGPCRs) are important therapeutic...
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