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OB/GYN General

CircRNA hsa_circ_0013958 may contribute to the development of ovarian cancer by affecting epithelial-mesenchymal transition and apoptotic signaling pathways.

Mar 12, 2020

CircRNA plays an important role in the development of tumors, but its mechanism of action in ovarian cancer is still unclear.The expression level of hsa_circ_0013958 in 45 pairs of ovarian cancer tiss...

KNDC1 Is a Predictive Marker of Malignant Transformation in Borderline Ovarian Tumors.

Mar 12, 2020

Few screening markers for malignant transformation in borderline ovarian tumors (BOT) have been clearly established. The kinase noncatalytic C-lobe domain containing 1 (KNDC1), a brain-specific Ras gu...

Astragalus polysaccharides inhibits ovarian cancer cell growth via microRNA-27a/FBXW7 signaling pathway.

Mar 12, 2020

Astragalus polysaccharide (APS), a natural anti-oxidant found in Astragalus membranaceus emerging as a novel anticancer agent, exerts antiproliferative and pro-apoptotic activity in various cancer cel...

Use of an Online Breast Cancer Risk Assessment and Patient Decision Aid in Primary Care Practices.

Mar 12, 2020

U.S. Preventive Services Task Force (USPSTF) recommendations for mammography screening, genetic counseling and testing for pathogenic mutations, and use of risk-reducing medications require assessme...

The search for assisted reproduction: profile of patients seen in the fertility outpatient clinic of a public hospital.

Mar 12, 2020

To analyze the epidemiological profile of patients treated at the Fertility Outpatient Clinic of a tertiary public hospital in Juiz de Fora.This cross-sectional study analyzed the medical records of 4...

Evaluation of lumican effects on morphology of invading breast cancer cells, expression of integrins and downstream signaling.

Mar 12, 2020

The small leucine-rich proteoglycan (SLRP) lumican regulates estrogen receptors (ERs)-associated functional properties of breast cancer cells, expression of matrix macromolecules and epithelial-to-mes...

Time to diagnostic resolution after an uncertain screening mammogram in an underserved population.

Mar 12, 2020

Screening mammography has reduced breast cancer-associated mortality worldwide. Approximately 10% of patients require further diagnostic testing after an uncertain screening mammogram (Breast imaging ...

Can VEGFR-3 be a better tumor marker for breast cancer than CA 15-3?

Mar 12, 2020

Vascular Endothelial Growth Factor Receptor 3 (VEGFR-3) is a very important factor which promotes lymphangiogenesis not only in physiological but also in pathological processes in which we can include...

MYC Dysregulates Mitosis, Revealing Cancer Vulnerabilities.

Mar 12, 2020

Tumors that overexpress the MYC oncogene are frequently aneuploid, a state associated with highly aggressive cancers and tumor evolution. However, how MYC causes aneuploidy is not well understood. Her...

Characterizing infection in anti-neutrophil cytoplasmic antibody-associated vasculitis: results from a longitudinal, matched-cohort data linkage study.

Mar 12, 2020

Infection exerts a major burden in ANCA-associated vasculitis (AAV), however, its precise extent and nature remains unclear. In this national study we aimed to longitudinally quantify, characterize an...

HPV-Related Multiphenotypic Sinonasal Carcinoma: A Case Report and Literature Review.

Mar 12, 2020

Human papilloma virus-related multi phenotypic sinonasal carcinoma (HMSC), a recently characterized sinonasal malignancy, is discussed including histology, clinical presentation, and treatment outcome...

In RRP, serologic response to HPV is frequently absent and slow to develop.

Mar 12, 2020

Recurrent respiratory papillomatosis (RRP) is characterized by repeated formation of papillomas in the respiratory tract and is caused by human papillomavirus (HPV) types 6 and 11. Women with genital ...

Bacterial vaginosis, representation of endocervical and/or metaplastic cells, and cytological abnormalities in different age groups: Association study.

Mar 12, 2020

Studies have indicated that bacterial vaginosis (BV) might be a cofactor for the acquisition and persistence of high-risk papillomavirus, enabling the development of cytological abnormalities. The pre...

Association of Aspirin with Hepatocellular Carcinoma and Liver-Related Mortality.

Mar 12, 2020

More information is needed about the long-term effects of low-dose aspirin (≤160 mg) on incident hepatocellular carcinoma, liver-related mortality, and gastrointestinal bleeding in persons with chro...

Development of a Multicriteria Decision Analysis Framework for Evaluating and Positioning Oncologic Treatments in Clinical Practice.

Mar 12, 2020

Several frameworks have been developed to define and quantify the value of oncologic therapies and to support decision making; however, they define treatment value mainly in terms of clinical benefit....

Mood sensitivity to estradiol predicts depressive symptoms in the menopause transition.

Mar 12, 2020

The risk for depression markedly rises during the 5-6 years leading up to the cessation of menstruation, known as the menopause transition. Exposure to extreme estradiol levels may help explain this i...

Mid-life predictors of late-life depressive symptoms; determining risk factors spanning two decades in the Women's Heathy Ageing Project.

Mar 12, 2020

Data available from longitudinal studies of adequate duration to explore midlife risk factors for late life higher depressive symptom scores in women is lacking. This study examines midlife (mean ages...

Parity and incidence of thyroid autoimmunity a population-based study Tehran thyroid study (TTS).

Mar 12, 2020

Autoimmune thyroid disease (AITD) is the most common autoimmune disorder. Evidence regarding high prevalence and incidence of thyroid autoimmunity in women, and specially women of reproductive age, is...

Consumption of Nopal Powder in Adult Women.

Mar 12, 2020

Osteoporosis is a chronic disease in adult women caused by menopause and some other factors, which entails deficiency of calcium in diet. Natural products are the best source of nutriments to reduce t...

Establishment of reference intervals for immunoassay analytes of adult population in Saudi Arabia.

Mar 12, 2020

Background This is a second part of report on the IFCC global multicenter study conducted in Saudi Arabia to derive reference intervals (RIs) for 20 immunoassay analytes including five tumor makers, f...

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