Advertisement

STDs

"Potential entry receptors for human γ-herpesvirus into epithelial cells: a plausible therapeutic target for viral infections".

Nov 22, 2021

Herpesviruses are ubiquitous viruses, specifically the Epstein Barr virus (EBV). EBV and Kaposi's sarcoma-associated herpesvirus (KSHV) establish their latency for a long period in B-cells and their r...

Effective HPV vaccination coverage in Australia by number of doses and two-dose spacing: what if one or two doses are sufficient?

Apr 19, 2021

Initially, three-dose schedules were recommended for vaccines against human papillomavirus (HPV); subsequently recommendations have been updated to a schedule of two doses delivered at least six (mini...

Improved outcome prediction of oropharyngeal cancer by combining clinical and MRI features in machine learning models.

Apr 19, 2021

New markers are required to predict chemoradiation response in oropharyngeal squamous cell carcinoma (OPSCC) patients. This study evaluated the ability of magnetic resonance (MR) radiomics to predict ...

Combining immunotherapy with an epidrug in squamous cell carcinomas of different locations: rationale and design of the PEVO basket trial.

Apr 19, 2021

Squamous cell carcinomas (SCCs) are among the most frequent solid tumors in humans. SCCs, related or not to the human papillomavirus, share common molecular features. Immunotherapies, and specifically...

CME: Risk of Oral HPV Among Female Adolescents

Jul 01, 2020

This course discusses a study that assessed the risk factors for oral HPV, as well as the association of HPV vaccination with HPV prevalence in the oral cavity, in sexually active female adolescents r...

Microglia influence host defense, disease, and repair following murine coronavirus infection of the central nervous system.

May 26, 2020

The present study examines functional contributions of microglia in host defense, demyelination, and remyelination following infection of susceptible mice with a neurotropic coronavirus. Treatment wit...

Cost minimization analysis and validation of a cytomegalovirus quantitative in-house real time PCR assay in relation to m2000 RealTime System.

May 26, 2020

Cytomegalovirus (CMV) causes severe diseases in the immunocompromised patients. Nowadays, quantitative polymerase chain reaction (qPCR) is the gold-standard for diagnosis and monitoring of CMV infecti...

Treatment with Foscarnet after Allogeneic Hematopoietic-Cell Transplant (AlloHCT) is Associated with Long-Term Loss of Renal Function.

May 26, 2020

Despite a well-established risk of chronic kidney disease (CKD) after allogeneic hematopoietic cell transplant (AlloHCT), the benefits of using nephrotoxic anti-infective agents to treat serious peri-...

Omega-3 derivatives, specialized pro-resolving mediators: Promising therapeutic tools for the treatment of pain in chronic liver disease.

May 26, 2020

The main causes of liver injury are associated with inflammation and permanent damage. They can cause chronic liver disease (CLD), which is mainly related to viral hepatitis, alcohol consumption and n...

FOXA1-induced LINC01207 facilitates head and neck squamous cell carcinoma via up-regulation of TNRC6B.

May 26, 2020

Head and neck squamous cell carcinoma (HNSCC) is a common cancer in China, which was mainly caused by smoking and HPV infection. With the advancement of molecular research, it is meaningful to explore...

Insights into herpesvirus assembly from the structure of the pUL7:pUL51 complex.

May 12, 2020

Herpesviruses acquire their membrane envelopes in the cytoplasm of infected cells via a molecular mechanism that remains unclear. Herpes simplex virus (HSV)-1 proteins pUL7 and pUL51 form a complex re...

Hepatitis C Virus Infection and Treatment as Independent Prognostic Factors in Diffuse Large B-Cell Lymphoma Egyptian Patients.

May 12, 2020

Egypt is one of highest hepatitis C virus (HCV) endemic areas. Chronic HCV infection has extra-hepatic manifestations, including non-Hodgkin lymphoma (NHL). Diffuse large B-cell lymphoma (DLBCL) is co...

Hepatitis C Screening Rates and Care Cascade in a Large US Insured Population, 2010-2016: Gaps to Elimination.

May 12, 2020

Understanding the health care system's ability to move patients through the hepatitis C virus (HCV) care cascade from screening to treatment is essential for HCV elimination. This retrospective study ...

Population-based study of autoimmune hepatitis and primary biliary cholangitis in Germany: rising prevalences based on ICD codes, yet deficits in medical treatment.

May 12, 2020

 Population-based data on the prevalence of and real-life treatment for the autoimmune liver diseases (AILD), primary biliary cholangitis (PBC) and autoimmune hepatitis (AIH), are scarce, and such k...

Successful fourth line treatment of a relapse patient with chronic hepatitis C virus infection genotype 3a using sofosbuvir, glecaprevir/pibrentasvir, and ribavirin: a case report.

May 12, 2020

 Relapses after therapy with direct-acting antiviral agents (DAA) in chronic hepatitis C virus (HCV) infections are rare due to high efficacy of interferon-free therapy regimens. The presence of res...

Prediction of liver fibrosis severity in alcoholic liver disease by human microfibrillar-associated protein 4.

Apr 28, 2020

Alcoholic liver disease (ALD) is a public health concern that is the cause of half of all cirrhosis-related deaths. Early detection of fibrosis, ideally in the pre-cirrhotic stage, is a key strategy f...

Effect of duck hepatitis A virus genotype 3 infection on glucose metabolism of Pekin ducklings and underlying mechanism.

Apr 28, 2020

Earlier works identified the second generation (Z8R2) of a resistant Pekin duck line to duck hepatitis A virus genotype 3 (DHAV-3), which displays significantly strong resistance than that of the seco...

Hepatitis B virus seroepidemiology data for Africa: Modelling intervention strategies based on a systematic review and meta-analysis.

Apr 22, 2020

International Sustainable Development Goals (SDGs) for elimination of hepatitis B virus (HBV) infection set ambitious targets for 2030. In African populations, infant immunisation has been fundamental...

Prognostic significance of neutrophil-to-lymphocyte ratio in HPV status era for oropharyngeal cancer.

Apr 22, 2020

To evaluate the role of baseline neutrophil-to-lymphocyte ratio (NLR) as prognostic marker in squamous cell carcinoma of the oropharynx (OPC) treated with definitive chemo-radiotherapy (CRT) in the er...

Prevalence, incidence and associated factors for HBV infection among male and female prisoners in Central Brazil: a multicenter study.

Apr 22, 2020

Prison population are at high risk for hepatitis B virus (HBV) infection. The aim of this study was to assess the prevalence, incidence, HBV associated factors and the circulating genotypes/subtypes.A...