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Macular Degeneration

Single subcutaneous injection of the minocycline nanocomposite-loaded thermosensitive hydrogel for the effective attenuation of experimental autoimmune uveitis.

May 23, 2022

Autoimmune uveitis induces a serious pathological and inflammatory response in the retina/choroid and results in vision impairment and blindness. Here, we report a minocycline (Mino) nanocomposite-loa...

[Ocular abnormalities of children born prematurely at the Yaoundé Gynaeco-Obstetrics And Pediatric Hospital].

May 23, 2022

To identify ocular abnormalities in premature children in order to treat reversible visual disorders and help prevent low vision and blindness in this population at risk.This was a cross-sectional, an...

Acute Angle Closure Attacks Are Uncommon in Primary Angle-Closure Suspects: The Zhongshan Angle Closure Prevention Trial.

May 16, 2022

Angle-closure glaucoma is a major cause of blindness worldwide that carries an excess risk of severe, bilateral visual impairment. A common concern among clinicians is precipitating acute angle closur...

The impact of low vision on social function: The potential importance of lost visual social cues.

May 16, 2022

Visual cues usually play a vital role in social interaction. As well as being the primary cue for identifying other people, visual cues also provide crucial non-verbal social information via both faci...

The Peter Watson Memorial Lecture "Vision for the World".

Apr 11, 2022

In the 1990s attention was drawn to the huge global problem of blindness and vision loss; most of which was unnecessary, being preventable or treatable. This led to the global initiative, Vision 2020....

Amaurosis as an initial presentation of Takayasu arteritis in children.

Apr 04, 2022

Visual disturbances in Takayasu arteritis (TA) are common but tend to be late manifestations of the disease. However, its presence at diagnosis must alert TA to avoid sight disabilities. Herein, we pr...

Automated method for real-time AMD screening of fundus images dedicated for mobile devices.

Mar 21, 2022

Aged macular degeneration (AMD) leads to a progressive decline in visual acuity until reaching blindness. It is considered as an irreversible pathology where an early diagnosis remains crucial. Howeve...

Photo-crosslinked hydrogels for tissue engineering of corneal epithelium.

Mar 14, 2022

The vast majority of patients with corneal blindness cannot recover their vision due to the serious shortage of donor cornea. However, the technology to construct a feasible corneal substitute is a pr...

A compound heterozygous mutation in the S-Antigen Visual Arrestin SAG gene in a Chinese patient with Oguchi type one: a case report.

Mar 07, 2022

Oguchi disease is a rare autosomal recessive form of congenital quiescent night blindness. Oguchi disease has been found to be associated with gene mutations in SAG and GRK1, which are vital factors i...

Disruption of miR-18a Alters Proliferation, Photoreceptor Replacement Kinetics, Inflammatory Signaling, and Microglia/Macrophage Numbers During Retinal Regeneration in Zebrafish.

Mar 07, 2022

In mammals, photoreceptor loss causes permanent blindness, but in zebrafish (Danio rerio), photoreceptor loss reprograms Müller glia to function as stem cells, producing progenitors that regenerate p...

Evaluations of Deep Learning Approaches for Glaucoma Screening Using Retinal Images from Mobile Device.

Feb 28, 2022

Glaucoma is a silent disease that leads to vision loss or irreversible blindness. Current deep learning methods can help glaucoma screening by extending it to larger populations using retinal images. ...

Cost-effectiveness of artificial intelligence screening for diabetic retinopathy in rural China.

Feb 28, 2022

Diabetic retinopathy (DR) has become a leading cause of global blindness as a microvascular complication of diabetes. Regular screening of diabetic retinopathy is strongly recommended for people with ...

Dexamethasone Implant for Diabetic Macular Oedema: 1-Year Treatment Outcomes from the Fight Retinal Blindness! Registry.

Feb 21, 2022

Phase III clinical trials of dexamethasone intravitreal implant for diabetic macular oedema (DMO) have reported significant improvements in visual acuity (VA). Studies evaluating the treatment of DMO...

Risk factors, causative organisms and sensitivity patterns of infective keratitis in a tertiary care hospital in Rawalpindi.

Feb 14, 2022

To determine the risk factors, causative organisms, sensitivity patterns and treatment outcomes of infective corneal ulcers.The prospective cohort study was conducted from January 2018 to December 201...

Gene polymorphisms of TLR10: Effects on bacterial meningitis outcomes in Angolan children.

Feb 07, 2022

This study examined whether gene polymorphisms for toll-like receptor 10 (TLR10) associated with the susceptibility to and outcomes of bacterial meningitis (BM) in Angolan children. The study cohort c...

Ocular and cerebral causes of visual impairment in young children and a new scoring system to evaluate visual function.

Jan 31, 2022

Childhood blindness is important cause contributing to the burden of blindness. It is necessary to identify the most frequently observed diseases in different populations. We aimed to demonstrate clin...

Development of Bromfenac Sodium loaded Pluronic Nanomicelles: Characterization and Corneal permeation study.

Jan 31, 2022

The Cataract isleading cause of visual impairment and preventable blindness worldwide. Cataract removal surgery involves various post-operative complications like pain and inflammation.To screen the p...

OPA1 Modulates Mitochondrial Ca Uptake Through ER-Mitochondria Coupling.

Jan 24, 2022

Autosomal Dominant Optic Atrophy (ADOA), a disease that causes blindness and other neurological disorders, is linked to mutations. OPA1, dependent on its GTPase and GED domains, governs inner mitocho...

Arguments for 'ocular donation' as standardised terminology to reduce the 'ick factor' of 'eye donation'.

Jan 10, 2022

This brief report presents the global problem of the shortfall of donor corneal tissue for transplantation, a potential root cause ('ick factor' language), and a potential solution (modification of 'i...

Group identity in blindness groups predicts life satisfaction and lower anxiety and depression.

Jan 03, 2022

Group disability identity (GDI) refers to feelings of connection to the disability community. Researchers have proposed that disability identity protects against disability-related stressors. However,...