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Orthopedics General

Osteosarcoma: Novel prognostic biomarkers using circulating and cell-free tumour DNA.

Apr 18, 2022

Osteosarcoma (OS) is the most common primary bone tumour in children and adolescents. Circulating free (cfDNA) and circulating tumour DNA (ctDNA) are promising biomarkers for disease surveillance and ...

Assessment of complications associated with casting of acute distal radius fractures in adults.

Apr 11, 2022

Controversy exists regarding the closed treatment of distal radius fractures. Circumferential casting of acute distal radius fractures has been shown to be safe in children, however, little research h...

Higher stress and symptom severity are associated with worse depressive symptom profiles in patients receiving chemotherapy.

Apr 11, 2022

In a sample of oncology patients, identify subgroups of patients with distinct depressive symptom profiles and evaluate for differences in demographic and clinical characteristics, levels of stress an...

Lived experience of State-sponsored intra-national overseas therapeutic mobility for stem cell transplantation.

Apr 11, 2022

This article focuses on the lived experience of patients with haematological cancer who were transferred from La Réunion (a French overseas Department) to mainland France to undergo allogeneic haemat...

How we approach the treatment of patients with high-risk neuroblastoma with naxitamab: experience from the Hospital Sant Joan de Déu in Barcelona, Spain.

Apr 11, 2022

Naxitamab [humanized 3f8 (hu3F8)] is a humanized monoclonal antibody (mAb) targeting the disialoganglioside GD2. It was approved in 2020 by the United States Food and Drug Administration (FDA) in com...

Methodological Considerations for Investigating Iron Status and Regulation in Exercise and Sport Science Studies.

Apr 04, 2022

Iron deficiency is a common health issue in active and athlete populations. Accordingly, research into iron status, regulation, absorption, and iron deficiency treatment strategies is increasing at a ...

Numerical modelling of cancellous bone damage using an orthotropic failure criterion and tissue elastic properties as a function of the mineral content and microporosity.

Apr 04, 2022

Elastic and strength properties of lamellar tissue are essential to analyze the mechanical behaviour of bone at the meso- or macro-scale. Although many efforts have been made to model the architecture...

Vertical root fractures in root treated teeth-current status and future trends.

Mar 28, 2022

Vertical root fracture (VRF) is a common reason for the extraction of root filled teeth. The accurate diagnosis of VRF may be challenging due to the absence of clinical signs, whilst conventional radi...

Blue light potentiates safety and bactericidal activity of p-Toluquinone.

Mar 28, 2022

Fewer antibiotics are available for effective management of bacterial infections to date owing to increasing multiple-drug resistance (MDR). Here, we expand our early success in combination of 405 nm...

Recombinant guanosine-5'-triphosphate (GTP)-binding protein associated with Poloxamer 407-based polymeric micelles protects against Leishmania infantum infection.

Mar 28, 2022

Leishmania virulence proteins should be considered as vaccine candidates against disease, since they are involved in developing infection in mammalian hosts. In a previous study, a Leishmania guanosin...

Adjustable-loop cortical suspension device for posterolateral corner reconstruction in the setting of fibular avulsion fracture: a case series and novel technique description.

Mar 21, 2022

A novel technique using an adjustable-loop cortical suspension toggle device for reduction of a fibular head avulsion fracture (arcuate fracture) in posterolateral corner (PLC) reconstruction is descr...

Arthroscopic fixation for tibial eminence fractures: A clinical retrospective study of cannulated screws versus transosseous anchor knot fixation techniques with suture anchors.

Mar 21, 2022

A variety of different techniques or methods for treatment of tibial eminence fracture (TEF) have been reported, but there is still controversy on the optimum choice for treating TEFs. The aim of the ...

Osgood-Schlatter Disease in youth elite football: Minimal time-loss and no association with clinical and ultrasonographic factors.

Mar 21, 2022

Osgood-Schlatter Disease is the most common cause of knee pain in youth. Scientific research in youth elite football is limited.To assess clinical and ultrasonographic factors associated with Osgood-S...

Computed Tomographic Features of Non-Lame French Bulldog Elbows.

Mar 14, 2022

 French Bulldogs are predisposed to humeral condylar fractures. Computed tomography (CT) in English Springer Spaniel elbows has allowed identification of humeral intracondylar fissures (HIF), which ...

Pumping the Periosteum: A Feasibility Study: Periosteal Distraction Osteogenesis in a Rat Model.

Mar 14, 2022

Gradual elevation of periosteum from the bone surface is known to promote the adaptation of soft tissues and the formation of hard tissues. The aim of our study was to estimate the benefit of perioste...

With Lacking Data, Estimating The Oswestry Disability Index Measurement Error

Mar 11, 2022

The Oswestry Disability Index (ODI) was the most often used patient-reported outcome measure for low back pain. Incomplete ODI questionnaires can lead to measurement errors, leading to misclassificati...

After Single-Level Posterior Lumbar Interbody Fusion, Risk Factors For Early-Onset Radiographical Adjacent Segment Disease in Patients With Spondylolysis Spondylolisthesis

Mar 11, 2022

For a study, the researchers sought to determine any risk variables for radiographic ASD in individuals who had single-level PLIF for L5–S1 spondylolysis spondylolisthesis. The researchers conducted...

Computed Tomography Evaluation of Bone Mineral Density After Instrumented Lumbar Fusion

Mar 11, 2022

The measurement of Hounsfield Units (HU) by computed tomography (CT) has been reported as a technique for determining Bone Mineral density (BMD). The BMD of the UIV was useful for surgical planning fo...

Validity of the Training-Load Concept.

Mar 07, 2022

Training load (TL) is a widely used concept in training prescription and monitoring and is also recognized as as an important tool for avoiding athlete injury, illness, and overtraining. With the wide...

Conservative management of Jones fractures with immediate weight-bearing in a walking boot demonstrates healing.

Feb 28, 2022

Jones fractures, or proximal metatarsal fractures at the level of the fourth and fifth intermetatarsal junction, have a high risk for nonunion due to a vascular watershed region. Classically, treatmen...

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