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Orthopedics General

Comparing metabolic profiles between endurance athlete and non-athlete females reveals differences in androgenic and corticosteroids levels.

Feb 21, 2022

Endurance training is associated with physiological changes in elite athletes, but little is known about female-specific effects of endurance training. Despite the significant rise in female sports pa...

Inhibition of gene expression and production of iNOS and TNF-α in experimental model of neurodegenerative disorders stimulated microglia by Soy nano-isoflavone/stem cell-exosomes.

Feb 21, 2022

The present study evaluated the therapeutic potential of soybean nano-isoflavone extract versus bone marrow mesenchymal stem cells derived extracellular exosomes (BMSCs-EXs) in experimentally induced ...

Assessing the clinical utility of volumetric HRCT in pediatric enlarged vestibular aqueduct related hearing loss.

Feb 21, 2022

|The aim of this study was to evaluate the use of volumetric HRCT measurements in the diagnosis of enlarged vestibular aqueduct syndrome (EVAS) and describe the association of this novel radiographic ...

Mechanical properties of cracked articular cartilage under uniaxial creep and cyclic tensile loading.

Feb 14, 2022

Cracks may change the mechanical properties of articular cartilage, and further lead to early osteoarthritis. The study aimed to probe the mechanical properties of cracked cartilage under uniaxial ten...

Asiatic Acid Induces Mitochondrial Apoptosis via Inhibition of JAK2/STAT3 Signalling Pathway in Human Osteosarcoma.

Feb 14, 2022

Osteosarcoma (OS), a severe malignant bone tumour, usually occurs in adolescents and children and has a poor prognosis. Asiatic acid (AA), an active component isolated from Centella asiatica (L.) Urb....

Does cage position affect the risk of cage subsidence after oblique lumbar interbody fusion in the osteoporotic lumbar spine: a finite element analysis.

Feb 07, 2022

This study aimed to evaluate the biomechanical effects of different cage positions with stand-alone (SA) methods and bilateral pedicle screw fixation (BPSF) in the osteoporotic lumbar spine after OLIF...

Aluminum bone toxicity in infants may be promoted by iron deficiency.

Feb 07, 2022

Aluminum has adverse effects on human health. Aluminum is poorly transported from the gastrointestinal tract, but if the load is high, a significant level of aluminum may be absorbed. There are two ma...

Targeting Cancer-Associated Fibroblasts in the Bone Marrow Prevents Resistance to CART-Cell Therapy in Multiple Myeloma.

Jan 31, 2022

Pivotal clinical trials of B-cell maturation antigen (BCMA)-targeted chimeric antigen receptor (CAR) T-cell therapy in patients with relapsed/refractory multiple myeloma (MM) resulted in remarkable in...

Chronic low back pain is associated with impaired bed turning ability: Evaluation by a mobility detection system.

Jan 24, 2022

We aimed to assess and compare kinetics and kinematic variables of bed turning ability using a mobility detection system in patients with and without chronic low back pain and to observe the impacts o...

Arthroscopic debridement for infection after fracture fixation (IAFF) of the ankle: A case report.

Jan 24, 2022

Infection after fracture fixation (IAFF) is one of the most challenging issues for the lower-middle class socioeconomic. It is also related to unsatisfactory outcome of the treatment. Arthroscopy usua...

Reduced intensity hematopoietic stem cell transplantation for myelofibrosis in accelerated-phase.

Jan 24, 2022

Accelerated-phase (AP) myelofibrosis, currently defined by circulating blasts 10-19%, usually confers very high risk for progression and poor outcome. The outcome of hematopoietic stem cell transplant...

The diagnostic precision of computed tomography for traumatic cervical spine injury: An in vitro biomechanical investigation.

Jan 17, 2022

CT is considered the best method for vertebral fracture detection clinically, but its efficacy in laboratory studies is unknown. Therefore, our objective was to determine the sensitivity, precision, a...

Engagement in leisure activities and depression in older adults in the United States: Longitudinal evidence from the Health and Retirement Study.

Jan 17, 2022

Receptive cultural engagement (e.g. attending theaters and museums) can reduce depression in older adults. However, whether specific participatory leisure activities are associated with lower rates of...

Bone permeability and mechanotransduction: Some current insights into the function of the lacunar-canalicular network.

Jan 17, 2022

Lacunar-canalicular (LC) permeability involves the passage of fluids, nutrients, oxygen, ions, and signalling molecules through bone tissue, facilitating the maintenance of bone vitality and function ...

Robot-assisted ventral sacral Tarlov cystectomy; A case report.

Jan 10, 2022

Although asymptomatic Tarlov cysts (TCs) are reported in up to 13% of the population, symptomatic TCs are rare (less than 1%), making the management of the symptomatic cysts controversial. The most co...

Enzymatically functionalized RGD-gelatin scaffolds that recruit host mesenchymal stem cells in vivo and promote bone regeneration.

Jan 10, 2022

Critical-size bone defects are imposing a substantial biomedical burden. Despite being long regarded as a potential approach to mitigate this burden or an alternative to bone grafts, bone tissue engin...

Effects of organic macro and trace minerals in fast and slower growing broiler breeders' diet on offspring growth performance and tibia characteristics.

Jan 10, 2022

This study was designed to evaluate effects of source of macro and trace minerals (inorganic vs. organic) in fast and slower growing broiler breeders' diets on egg and hatchling mineral content and on...

Constraint of musculoskeletal tissue and path planning of robot-assisted fracture reduction with collision avoidance.

Jan 03, 2022

For the robot-assisted fracture reduction, due to the complex fracture musculoskeletal environment, it is necessary to consider the influence of soft tissue traction on preoperative reduction path pla...

Dual NMR for probing intrinsic bone structure and a potential gut-bone axis in ovariectomized rats.

Jan 03, 2022

Currently the existence of a gut-bone axis receives massive attention, and while sound premises and indirect proofs exist for the gut-bone axis concept, few studies have provided actual data linking t...

Interactions of B-lymphocytes and bone cells in health and disease.

Dec 27, 2021

Bone remodeling occurs through the interactions of three major cell lineages, osteoblasts, which mediates bone formation, osteocytes, which derive from osteoblasts, sense mechanical force and direct b...

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