Broad Institute of MIT and Harvard, Cambridge, MA, USA.

Broad Institute of MIT and Harvard, Cambridge, MA, USA.

Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.

The Koch Institute for Integrative Cancer Research at MIT, Cambridge, MA, USA.

Broad Institute of MIT and Harvard, Cambridge, MA, USA.

Broad Institute of MIT and Harvard, Cambridge, MA, USA.

Broad Institute of MIT and Harvard, Cambridge, MA, USA.

Department of Pediatrics, Harvard Medical School, Boston, MA, USA.

Division of Hematology/Oncology, Boston Children’s Hospital, Boston, MA, USA.

Department of Pediatric Oncology, Dana Farber Cancer Institute, Boston, MA, USA.

Broad Institute of MIT and Harvard, Cambridge, MA, USA.

Massachusetts Institute of Technology, Department of Health Sciences and Technology, Cambridge, MA, USA.

Broad Institute of MIT and Harvard, Cambridge, MA, USA.

Broad Institute of MIT and Harvard, Cambridge, MA, USA.

Broad Institute of MIT and Harvard, Cambridge, MA, USA.

Broad Institute of MIT and Harvard, Cambridge, MA, USA.

Broad Institute of MIT and Harvard, Cambridge, MA, USA. scarr@broad.mit.edu.

Broad Institute of MIT and Harvard, Cambridge, MA, USA. nhacohen@mgh.harvard.edu.

Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA. nhacohen@mgh.harvard.edu.

Center for Cancer Research, Massachusetts General Hospital, Boston, MA, 02114, USA. nhacohen@mgh.harvard.edu.