PubMed

Molecular neurodegeneration 2019 02 1514(1) 9 doi 10.1186/s13024-019-0310-z Abstract BACKGROUND A GC hexanucleotide repeat expansion in the noncoding region of C9orf72 is the major genetic cause of frontotemporal dementia and...

Frontiers in genetics 2019 01 229() 712 doi 10.3389/fgene.2018.00712 Abstract Amyotrophic lateral sclerosis (ALS) is the most common adult-onset motor neuron disease and is characterized by the degeneration of upper and lower...

Cell 2019 01 29() pii 10.1016/j.cell.2019.01.018 Abstract Cell size varies greatly between cell types, yet within a specific cell type and growth condition, cell size is narrowly distributed. Why maintenance of a cell-type...

Cell reports 26(6) 1585-1597.e4 pii 10.1016/j.celrep.2019.01.052 Abstract Spondweni virus (SPOV) is the flavivirus that is most closely related to Zika virus (ZIKV). Although SPOV causes sporadic human infections in Africa,...

Nature communications 2019 02 1310(1) 722 doi 10.1038/s41467-019-08676-2 Abstract Homologous recombination (HR) repairs DNA double-strand breaks (DSBs) to maintain genomic integrity. Recombinase recruited to the DSBs by the...

Advances in nutrition (Bethesda, Md.) 10(suppl_1) S31-S48 doi 10.1093/advances/nmy037 Abstract The consumption of sugar-free foods is growing because of their low-calorie content and the health concerns about products with high...

The Journal of clinical investigation 2019 02 12() doi 10.1172/JCI96313 Abstract Understanding the tumor immune microenvironment (TIME) promises to be key for optimal cancer therapy, especially in triple-negative breast cancer...

PeerJ 2019 02 057() e6273 doi 10.7717/peerj.6273 Abstract Background Low-carbohydrate, high-fat (LCHF) diets are useful for treating a range of health conditions, but there is little research evaluating the degree of...

Genome biology 2019 02 1120(1) 30 doi 10.1186/s13059-019-1644-0 Abstract BACKGROUND Alternative splicing is a key regulatory mechanism in eukaryotic cells and increases the effective number of functionally distinct gene...