In a study published in Circulation: Cardiovascular Imaging, Francesco Negri, MD, and colleagues evaluated the use of cardiac magnetic resonance (CMR) feature tracking to assess myocardial strain in subclinical HCM. They studied 38 patients with subclinical HCM and 42 healthy volunteers. Feature tracking analysis showed significant reductions in global radial, circumferential, and longitudinal strains in patients with subclinical HCM compared with controls. These differences persisted even in patients without structural or functional cardiac abnormalities. The feature tracking parameters demonstrated excellent diagnostic performance, with global radial strain achieving an area under the curve of 0.946 and optimal cut-off value of 40.43% (sensitivity 90.48%, specificity 94.44%). The researchers noted similar performance for global circumferential and longitudinal strains. The findings suggest CMR feature tracking-derived parameters can be used to identify subclinical HCM