The following is a summary of “Clinical performance and shape analysis of trifocal intraocular lenses via scanning electron microscopy,” published in the February 2024 issue of Ophthalmology by Yamashita et al.

Researchers started a retrospective study to compare visual performance and lens morphology between the TFNT and CNWT intraocular lenses via scanning electron microscopy (SEM).

They implanted the CNWT in eighteen patients (18 eyes) and the TFNT in twenty patients (20 eyes—excluded individuals with prior ocular surgeries, ocular pathologies, or corneal abnormalities. Postoperatively, examinations at 1 month were conducted, including manifest refraction; assessed refractive error and distance-corrected visual acuity (DCVA) at various distances; performed slit-lamp examinations; led defocus curve testing; and evaluated contrast sensitivity (CS). The shape of the TFNT and CNWT lenses was analyzed using SEM.

The results showed that the mean spherical equivalent was 0.11 ± 0.41 D (CNWT group) and 0.12 ± 0.34 D (TFNT group) at 1-month post-operation. The two groups had no significant differences in the DCVA and defocus curve. CS was notably higher in the CNWT group than the TFNT group at spatial frequencies of 6 cycles per degree (cpd). Examination of the IOLs with SEM revealed that the CNWT group exhibited enhanced diffraction structure and edge processing accuracy compared to the TFNT group.

Investigators concluded that while visual acuity and defocus curves were similar, the CNWT group exhibited superior CS, suggesting IOL surface features may influence this outcome.

Source: bmcophthalmol.biomedcentral.com/articles/10.1186/s12886-024-03355-3