Research indicates that non-Hispanic black (NHB) patients, especially men, are at a greater risk...Read More
MCT2 overexpression rescues metabolic vulnerability and protects retinal ganglion cells in two models of glaucoma.
Improving cellular access to energy substrates is one strategy to overcome observed declines in energy production and utilization in the aged and pathologic central nervous system. Monocarboxylate transporters (MCTs), the movers...Read More
A directed network analysis of the cardiome identifies molecular pathways contributing to the development of HFpEF.
The metabolic syndrome and associated comorbidities, like diabetes, hypertension and obesity, have been implicated in the development of heart failure with preserved ejection fraction (HFpEF). The molecular mechanisms underlying...Read More
ACEI/ARB Use and Risk of Infection or Severity or Mortality of COVID-19: A Systematic Review and Meta-analysis.
We have sparse knowledge of the effects of angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) on the risk of COVID-19 infection and the progression of this disease. We systematically...Read More
Pseudotumor cerebri syndrome (PTCS) is a rare condition in children presenting with headache and papilledema from increased intracranial pressure that can cause significant morbidity. This can be idiopathic, also known as...Read More
Central Venous Obstruction-Induced Intracranial Hypertension in Hemodialysis Patients: An Underrecognized Cause of Elevated Intracranial Pressure.
Central venous obstruction (stenosis or occlusion) is common in patients with renal failure on hemodialysis and may be associated with intracranial hypertension (IH). Causes include vein injury from an endoluminal device, lumen...Read More
To analyse the relationship between stent expansion criteria using optical coherence tomography (OCT) analysis and the final PCI functional result.This post-hoc analysis of the DOCTORS study included non-ST elevation segment ACS...Read More
Identification of candidate lncRNAs and circRNAs regulating WNT3/β-catenin signaling in essential hypertension.
Mounting evidence suggests that noncoding RNAs (ncRNAs) contribute to the pathogenesis of cardiovascular diseases. However, their role in essential hypertension (EH) is still unclear. We therefore identified differentially...Read More
Oral glucocorticoids and incidence of hypertension in people with chronic inflammatory diseases: a population-based cohort study.
Only a few population-based studies have examined the association between glucocorticoids and hypertension, with inconsistent results. We aimed to investigate the effect of oral glucocorticoids on incidence of hypertension in...Read More