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Congestive Heart Failure

Current management and recent progress in desmoid tumors.

Apr 25, 2022

Desmoid tumors are rare soft tissue tumors that can have aggressive infiltrative growth and relapse locally. Desmoid tumors can impact functionality and cause treatment-related morbidity and mortality...

Glucose infusion suppresses acute restraint stress-induced peripheral and central sympathetic responses in rats.

Feb 28, 2022

Acute restraint stress (RS) induces sympathetic activation such as elevating plasma catecholamines, resulting in increase in blood glucose. We aimed to investigate whether glucose infusion affects the...

Elevation transposition method for superficialization of the basilic vein achieves better patency rate than tunnel transposition.

Oct 25, 2021

To compare the tunnel transposition and elevation transposition methods used for superficialization of the basilic vein in terms of complication and patency rates.This retrospective study included pat...

Impact of major infections on 10-year mortality after revascularization in patients with complex coronary artery disease.

Aug 12, 2021

The significant interaction between major infection and 5-year mortality after percutaneous coronary intervention (PCI) or coronary artery bypass graft (CABG) for complex coronary artery disease (CAD)...

Imbalance between the circulating endothelium-derived apoptotic microparticles and the endothelial colony-forming units of progenitor cells in patients undergoing diagnostic coronary angiography.

Aug 12, 2021

The involvement of the circulating endothelium-derived microparticles (EMPs) and the endothelial progenitor cells (EPCs) has been shown in the pathogenesis of coronary artery disease (CAD). The curren...

Perioperative Tranexamic Acid for ACTH-secreting Pituitary Adenomas: Implementation Protocol Results & Trial Prospectus.

Jul 08, 2021

Primary resection of ACTH-secreting pituitary adenoma has become a front-line standard-of-care treatment for Cushing disease. However, surgical intervention can be challenging due to elevated blood pr...

Modifying Diet and Exercise in MS (MoDEMS): Study design and protocol for a telehealth weight loss intervention for adults with obesity & Multiple Sclerosis.

Jul 05, 2021

Weight loss improves overall health, and reduces inflammation, risk of stroke, heart attack, diabetes, certain cancers, and death among individuals with obesity. Weight loss also improves mobility, in...

Management of Cardiac Sarcoidosis Using Mycophenolate Mofetil as a Steroid Sparing Agent.

Jun 28, 2021

Cardiac sarcoidosis (CS) is a major cause of morbidity and mortality in patients with systemic sarcoidosis. Steroid sparing agents are increasingly used, despite lack of randomized trials or published...

Peroxiredomin-4 ameliorates lipotoxicity-induced oxidative stress and apoptosis in diabetic cardiomyopathy.

Jun 17, 2021

Diabetic cardiomyopathy (DCM), one severe complication in the diabetes, leads to high mortality in the diabetic patients. However, the understanding of molecular mechanisms underlying DCM is far from ...

A computational pipeline for data augmentation towards the improvement of disease classification and risk stratification models: A case study in two clinical domains.

Jun 14, 2021

Virtual population generation is an emerging field in data science with numerous applications in healthcare towards the augmentation of clinical research databases with significant lack of population ...

evaluation of two adaptive Starling-like control algorithms for left ventricular assist devices.

Jun 03, 2021

The implantation of a left ventricular assist device (LVAD) is often the only therapy in terminal heart failure (HF). However, despite technical advancements, the physical fitness of the patients is s...

Cis-epistasis at the LPA locus and risk of cardiovascular diseases.

Apr 22, 2021

Coronary artery disease (CAD) has a strong genetic predisposition. However, despite substantial discoveries made by genome-wide association studies (GWAS), a large proportion of heritability awaits id...

Clinical application of computed tomography angiography and fractional flow reserve computed tomography in patients with coronary artery disease: A meta-analysis based on pre- and post-test probability.

Apr 19, 2021

To assess the diagnostic role of coronary computed tomography angiography (CCTA) and fractional flow reserve computed tomography (FFRCT) in confirming or excluding ischemic coronary artery disease (CA...

The Prevalence of Noonan Spectrum Disorders in Pediatric Patients with: Pulmonary Valve Stenosis.

Apr 05, 2021

To investigate the prevalence of Noonan spectrum disorders in a pediatric population with pulmonary valve stenosis (PVS) and explore other characteristics of NSD associated with PVS.A retrospective me...

Prognostic role of left ventricular apical aneurysm in hypertrophic cardiomyopathy: A systematic review and meta-analysis.

Apr 05, 2021

The aim of this study was to systematically review and quantitatively synthesize existing evidence about the prognostic value of LV apical aneurysm in patients with HCM.Hypertrophic cardiomyopathy (HC...

Advances in cirrhotic cardiomyopathy.

Mar 25, 2021

Cirrhotic cardiomyopathy (CCM) is a well-recognized entity. When patients with CCM encounter challenges such as liver transplantation, overt cardiac dysfunction manifests, leading to morbidity and mor...

Prevalence of Cardiac Arrhythmias and Distal Conduction Disorders in Patients With Chronic Chagas' Disease and Elevated Autoantibodies Against M2 Muscarinic Acetylcholine Receptors.

Mar 22, 2021

Chagas' disease (ChD) is a parasitic disease endemic to regions of Latin America and with an increasingly global reach. Up to 30% of patients with ChD develop severe dilated cardiomyopathy, ventricula...

Ectopic Burden via Holter Monitors in Friedreich Ataxia.

Mar 04, 2021

Friedreich ataxia is the most commonly inherited ataxia; nearly 60% of deaths are cardiac in nature, with one in eight deaths due to arrhythmia. Additional or irregular heartbeats, measured as ectopy,...

The role of selenium in cell survival and its correlation with protective effects against cardiovascular disease: A literature review.

Dec 21, 2020

Selenium is a trace element that provides protection against cellular damage and death. Previous research using several types of cells identified anti-oxidant, anti-inflammatory, and anti-apoptotic ef...

Dilated cardiomyopathy in a patient with autosomal dominant EEF1A2-related neurodevelopmental disorder.

Dec 14, 2020

The EEF1A2 gene encodes eukaryotic translation elongation factor 1α2, an integral component of the elongation factor complex. Heterozygous pathogenic variants in EEF1A2 are associated with neurodevel...