Head Trauma

Oxidative stress and inflammation play important roles in neuronal injury caused by intracerebral hemorrhage (ICH). Uric acid (UA), as an important natural antioxidant, may reduce neuronal injury caused by ICH. Delineating the...

As mitigation of brain aging continues to be a key public health priority, a wholistic and comprehensive consideration of the aging body has identified immunosenescence as a potential contributor to age-related brain injury and...

An accurate prognosis on the outcome of brain-injured patients with disorders of consciousness (DOC) remains a significant challenge, especially in the acute stage. In this study, we applied a multiple-technique approach to...

Spinal cord decellularized scaffolds can promote axonal regeneration and restore hindlimb motor function of spinal cord defect rats. However, Scarring caused by damage to the astrocytes at the margin of injury can hinder axon...

On the battlefields of Syria, many innocent civilians have been killed or injured by sarin poisoning. In Malaysia in February 2017, a North Korean man was assassinated with VX at Kuala Lumpur International Airport. In the face...

Neurofilament proteins as biomarkers of axonal degeneration have the potential to improve our capacity to predict and monitor neurological outcome in experimental autoimmune encephalitis (EAE), a model of multiple sclerosis...

Spinal cord injury (SCI) induces a secondary degenerative response that causes the loss of spared axons and worsens neurological outcome. The complex molecular mechanisms that mediate secondary axonal degeneration remain poorly...