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OB/GYN General

Is There a Link Between Carotid Atherosclerosis and Idiopathic Overactive Bladder Among Women with Metabolic Syndrome?

Mar 02, 2020

To evaluate the association between increased intima-media thickness (IMT) and atherosclerotic carotid plaque (CP) with idiopathic overactive bladder syndrome (OAB) in women with metabolic syndrome (M...

Rapid transit in the left-sided colon is related to poor defecatory function at early period after stoma closure.

Mar 02, 2020

Sphincter-saving surgery (SSS) is the gold standard for rectal cancer surgery but results in a wide spectrum of bowel dysfunction. This study investigated the impact of colonic dysmotility on the inco...

Serum progesterone levels could predict diagnosis, completion and complications of miscarriage.

Mar 02, 2020

Low serum progesterone levels were strongly correlated with miscarriages in several publications and with completion of miscarriage in one paper. This study evaluated several parameters, predominantly...

Preimplantation Genetic Testing in Assisted Reproduction Technology.

Mar 02, 2020

A significant proportion of clinically recognized pregnancies end in miscarriage. About 50% of early pregnancy losses are due to chromosome abnormalities. In assisted reproduction technology (ART), a ...

Outcome of multiple cesarean sections in a tertiary maternity hospital in the United Arab Emirates: A retrospective analysis.

Mar 02, 2020

Outcome of multiple cesarean sections in a tertiary maternity hospital in the United Arab Emirates.To describe the operative outcomes, clinical findings, maternal morbidity and neonatal outcome associ...

'There is no choice apart from antibiotics…': Qualitative analysis of views on urinary infections in pregnancy and antimicrobial resistance.

Mar 02, 2020

Antimicrobial resistance (AMR) is a health risk as it can lead to life-threatening infections. There has been a rise in resistant urinary tract infections (UTIs) which is the most common infection in ...

Serum miR-125b levels associated with epithelial ovarian cancer (EOC) development and treatment responses.

Mar 02, 2020

Downexpression of miRs was associated with tumor development, progression, and metastasis. This study explored the levels of miR-125b in patients with and to assess its diagnostic value and monitor ...

Adenosine Inhibits Ovarian Cancer Growth Through Regulating RhoGDI2 Protein Expression.

Mar 02, 2020

This study aimed to investigate the effect of adenosine (Ado) on the growth of ovarian cancer and to explore the related mechanisms.The effect of Ado on the proliferation of A2780 human ovarian cancer...

Prenatal Biochemical Screening and a Woman's Long-Term Risk of Cancer: A Population-Based Cohort Study.

Mar 02, 2020

Some hormones measured in pregnancy are linked to certain hormone-sensitive cancers. We investigated whether routine serum screening in pregnancy is associated with a woman's subsequent risk of hormon...

CircMUC16 promotes autophagy of epithelial ovarian cancer via interaction with ATG13 and miR-199a.

Mar 02, 2020

Circular RNA (circRNA) has been proven to play a significant role in multiple types of cancer. However, the expression and role of circRNAs in epithelial ovarian cancer (EOC) remains elusive.CircRNA a...

Enlarged cardiophrenic lymph nodes predict disease involvement of the upper abdomen and the outcome of primary surgical debulking in advanced ovarian cancer.

Mar 02, 2020

The outcome of ovarian cancer patients is highly dependent on the success of primary debulking surgery in terms of post-operative residual disease. This study critically evaluates the clinical impact ...

Comparison of Sperm Telomere Length between Two Sperm Selection Procedures: Density Gradient Centrifugation and Zeta Potential.

Mar 02, 2020

Telomeres are particular sequences of DNA located at the end of the eukaryotic chromosomes that are essential for genome integrity. Telomere length in spermatozoa differs among males, as well as sperm...

Micronutrients in Support to The Carbon Cycle Activate Antioxidant Defences and Reduce Sperm DNA Damage in Infertile Men Attending Assisted Reproductive Technology Programs: Clinical Trial Study.

Mar 02, 2020

Micronutrients in support to the carbon cycle were shown to reduce sperm DNA damage both in animal models and infertile men. Besides supporting DNA methylation, their positive effect may be mediated b...

Correction of Arginine Metabolism with Sepiapterin-the Precursor of Nitric Oxide Synthase Cofactor BH-Induces Immunostimulatory-shift of Breast Cancer.

Mar 02, 2020

Immunotherapy is a first-line treatment for many tumor types. However, most breast tumors are immuno-suppressive and only modestly respond to immunotherapy. We hypothesized that correcting arginine me...

Inhibitory effects of ceramide kinase on Rac1 activation, lamellipodium formation, cell migration, and metastasis of A549 lung cancer cells.

Mar 02, 2020

Ceramide kinase (CerK) phosphorylates ceramide to ceramide-1-phosphate (C1P), a bioactive sphingolipid. Since the mechanisms responsible for regulating the proliferation and migration/metastasis of ca...

Environmental exposure to nonylphenol and cancer progression Risk-A systematic review.

Mar 02, 2020

Environmental exposure to nonylphenol (NP) can adversely affect human and wildlife health. A systematic review was conducted to evaluate the relationship between environmental NP exposure and cancer p...

Long-Term Outcomes of Immediate Autologous Breast Reconstruction for Breast Cancer Patients.

Mar 02, 2020

There is limited information on the oncological outcomes of immediate autologous breast reconstruction in the Asian population. This study aimed to evaluate the oncological outcomes of immediate one-s...

Discovery of T-1101 tosylate as a first-in-class clinical candidate for Hec1/Nek2 inhibition in cancer therapy.

Mar 02, 2020

Highly expressed in cancer 1 (Hec1) plays an essential role in mitosis and is correlated with cancer formation, progression, and survival. Phosphorylation of Hec1 by Nek2 kinase is essential for its m...

The incorporation of cationic property and immunopotentiator in poly (lactic acid) microparticles promoted the immune response against chronic hepatitis B.

Mar 02, 2020

Biodegradable microparticles (MPs) as vaccine adjuvants have sparked the passion of researchers in recent decades. However, it is still a huge challenge to develop an efficient vaccine delivery system...

High varicella-zoster virus susceptibility in Caribbean island populations: implications for vaccination.

Mar 02, 2020

In Caribbean island populations, varicella-zoster virus (VZV) infection is reported regularly among adolescents and adults. Among them, disease more often runs a severe course, causing a substantial b...

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