Prostate Cancer
Jul 20, 2022
The IsoPSA biomarker displays superior diagnostic accuracy in the early detection of prostate cancer, thereby helping to avoid unnecessary prostate biopsies. There is a growing population of pa...
May 16, 2022
Data on advanced prostate cancer (PCa) suggest more prior systemic therapies might reduce tumor immune responsiveness. In treatment-naïve primary PCa, recent work correlated intratumoral plasma cell ...
May 16, 2022
The study was aimed to determine the diagnostic yield and outcome of transrectal ultrasound-guided prostate biopsy (TRUSPB) in a cohort of Sri Lankan men. A prospective study was conducted among 333 (...
May 09, 2022
Accumulating evidence supports that prostate cancer stem-like cells (PCSCs) play significant roles in therapy resistance and metastasis of prostate cancer. Many studies also show that nitric oxide (NO...
May 02, 2022
Prognostic indicators, treatments, and survival estimates vary by cancer type. Therefore, disease-specific models are needed to estimate patient survival. Our primary aim was to develop models to esti...
Apr 25, 2022
The US Food and Drug Administration (FDA)-approved CELLSEARCH assay (Menarini Silicon Biosystems) for circulating tumor cells (CTCs) relies on expression of an epithelial cell adhesion molecule to enr...
Apr 25, 2022
Pleiotrophin (PTN) is a growth factor that appears to play an important role in prostate cancer growth and angiogenesis. We have previously shown that decreased PTN expression in human prostate cancer...
Apr 18, 2022
The prostate bed is one of the common sites of early recurrence of prostate cancer. The currently used PSMA ligands (Ga-PSMA-11 and Tc-PSMA) undergo early urinary clearance resulting in interfering ph...
Apr 11, 2022
Lutetium-177 (Lu) prostate-specific membrane antigen (Lu PSMA) is a novel targeted treatment for patients with metastatic castration-resistant prostate cancer (CRPC). The purpose of the study was to d...
Apr 11, 2022
Fluorescence imaging is increasingly being implemented in surgery. One of the drawbacks of its application is the need to switch back-and-forth between fluorescence- and white-light-imaging settings a...
Apr 04, 2022
Apalutamide plus androgen-deprivation therapy (ADT) has been approved for treatment of patients with metastatic castration-sensitive prostate cancer (mCSPC) based on data from phase 3 TITAN study. Thi...
Apr 04, 2022
Prostate cancer (PCa) progression is characterized by the emergence of resistance to androgen deprivation therapy (ADT). AKT/PKB has been directly implicated in PCa progression, often due to the loss ...
Mar 28, 2022
Systemic treatments for prostate cancer (PC) have significant side effects. Thus, newer alternatives with fewer side effects are urgently needed. Animal and human studies suggest the therapeutic poten...
Mar 28, 2022
Accurate and robust prostate segmentation in transrectal ultrasound (TRUS) images is of great interest for image-guided prostate interventions and prostate cancer diagnosis. However, it remains a chal...
Mar 14, 2022
The purpose of this study is to provide certain data on clinical outcome of primary androgen deprivation therapy in men over 80 years of age with localized high-risk prostate cancer. This study includ...
Mar 14, 2022
The present study was aimed to explore the prognostic value of long noncoding RNA SNHG11 in prostate cancer, study its expression, and assess its effect on tumor progression. One hundred and twenty pr...
Mar 07, 2022
Telomere shortening is linked to aging and may be associated with increased risk for cancer. Most cancer studies have used telomere length in leukocytes rather than in the target tissue of cancer orig...
Feb 28, 2022
This study investigated the impact of treatment intensification with upfront docetaxel (DOC) or abiraterone (ABI) plus prednisolone on survival outcomes in patients with metastatic castration-sensitiv...
Feb 21, 2022
Studies have demonstrated lower prevalence of prostate cancer among patients with spinal cord injury but more advanced stage at diagnosis. However, there is a lack of literature on prostate cancer scr...
Feb 21, 2022
To investigate the effect of radiation treatment at a high-volume center on overall survival in men with intermediate-risk prostate cancer.From 2004-2015, 430,347 patients with intermediate-risk prost...
