A novel computational approach that converted Goldmann visual field (GVF) data into quantitative volumetric measurements among patients with choroideremia aided quantification of peripheral visual function and assessment of disease progression, according to results published in Ophthalmology Science. Todd E. Scheetz, PhD, and colleagues developed a novel computational method to convert GVF data into quantitative measurements, enabling analysis of visual field loss over 238 visits in 56 male patients aged 5-76. The study traced GVF records and provided insight into visual field loss over decades despite varying protocols. The estimated mean age at disease onset was 12.6. Mean field volume loss was 6.8% per year based on exponential modeling. Field volume was more strongly correlated between eyes (r2=0.935) than best corrected visual acuity (r2=0.285).
