The relationship of tongue fat content and efficacy of uvulopalatopharyngoplasty in Chinese patients with obstructive sleep apnea.

Aug 28, 2023

Contributors: Bingjie Zhao,Zine Cao,Yushan Xie,Yewen Shi,Yitong Zhang,Shiyu Liu,Xi Chen,Lina Ma,Xiaoxin Niu,Yonglong Su,Yani Feng,Chunfeng Lian,Xiaoyong Ren,Haiqin Liu

To investigate the relationship between tongue fat content and severity of obstructive sleep apnea (OSA) and its effects on the efficacy of uvulopalatopharyngoplasty (UPPP) in the Chinese group.
Fifty-two participants concluded to this study were diagnosed as OSA by performing polysomnography (PSG) then they were divided into moderate group and severe group according to apnea hypopnea index (AHI). All of them were also collected a series of data including age, BMI, height, weight, neck circumference, abdominal circumference, magnetic resonance imaging (MRI) of upper airway and the score of Epworth Sleepiness Scale (ESS) on the morning after they completed PSG. The relationship between tongue fat content and severity of OSA as well as the association between tongue fat content in pre-operation and surgical efficacy were analyzed.Participants underwent UPPP and followed up at 3 month after surgery, and they were divided into two groups according to the surgical efficacy.
There were 7 patients in the moderate OSA group and 45 patients in the severe OSA group. The tongue volume was significantly larger in the severe OSA group than that in the moderate OSA group. There was no difference in tongue fat volume and tongue fat rate between the two groups. There was no association among tongue fat content, AHI, obstructive apnea hypopnea index, obstructive apnea index and Epworth sleepiness scale (all P > 0.05), but tongue fat content was related to the lowest oxygen saturation (r=-0.335, P < 0.05). There was no significantly difference in pre-operative tongue fat content in two different surgical efficacy groups.
This study didn’t show an association between tongue fat content and the severity of OSA in the Chinese group, but it suggested a negative correlation between tongue fat content and the lowest oxygen saturation (LSaO). Tongue fat content didn’t influence surgical efficacy of UPPP in Chinese OSA patients.
This study didn’t report on a clinical trial, it was retrospectively registered.

© 2023. BioMed Central Ltd., part of Springer Nature.

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ABOUT THE CONTRIBUTORS

Bingjie Zhao,Zine Cao,Yushan Xie,Yewen Shi,Yitong Zhang,Shiyu Liu,Xi Chen,Lina Ma,Xiaoxin Niu,Yonglong Su,Yani Feng,Chunfeng Lian,Xiaoyong Ren,Haiqin Liu
Bingjie Zhao

Department of Otorhinolaryngology Head and Neck Surgery, The Second Affiliated Hospital of Xi’an Jiaotong University, No.157, Xiwu Road, Xi’an, Shaanxi, 710004, China.

Zine Cao

Department of Otorhinolaryngology Head and Neck Surgery, The Second Affiliated Hospital of Xi’an Jiaotong University, No.157, Xiwu Road, Xi’an, Shaanxi, 710004, China.

Yushan Xie

Department of Otorhinolaryngology Head and Neck Surgery, The Second Affiliated Hospital of Xi’an Jiaotong University, No.157, Xiwu Road, Xi’an, Shaanxi, 710004, China.

Yewen Shi

Department of Otorhinolaryngology Head and Neck Surgery, The Second Affiliated Hospital of Xi’an Jiaotong University, No.157, Xiwu Road, Xi’an, Shaanxi, 710004, China.

Yitong Zhang

Department of Otorhinolaryngology Head and Neck Surgery, The Second Affiliated Hospital of Xi’an Jiaotong University, No.157, Xiwu Road, Xi’an, Shaanxi, 710004, China.

Shiyu Liu

School of Mathematics and Statistics, Xi’an Jiaotong University, No.28, Xianningxi Road, Xi’an, Shaanxi, 710049, China.

Xi Chen

Department of Otorhinolaryngology Head and Neck Surgery, The Second Affiliated Hospital of Xi’an Jiaotong University, No.157, Xiwu Road, Xi’an, Shaanxi, 710004, China.

Lina Ma

Department of Otorhinolaryngology Head and Neck Surgery, The Second Affiliated Hospital of Xi’an Jiaotong University, No.157, Xiwu Road, Xi’an, Shaanxi, 710004, China.

Xiaoxin Niu

Department of Otorhinolaryngology Head and Neck Surgery, The Second Affiliated Hospital of Xi’an Jiaotong University, No.157, Xiwu Road, Xi’an, Shaanxi, 710004, China.

Yonglong Su

Department of Otorhinolaryngology Head and Neck Surgery, The Second Affiliated Hospital of Xi’an Jiaotong University, No.157, Xiwu Road, Xi’an, Shaanxi, 710004, China.

Yani Feng

Department of Otorhinolaryngology Head and Neck Surgery, The Second Affiliated Hospital of Xi’an Jiaotong University, No.157, Xiwu Road, Xi’an, Shaanxi, 710004, China.

Chunfeng Lian

School of Mathematics and Statistics, Xi’an Jiaotong University, No.28, Xianningxi Road, Xi’an, Shaanxi, 710049, China. chunfeng.lian@xjtu.edu.cn.

Xiaoyong Ren

Department of Otorhinolaryngology Head and Neck Surgery, The Second Affiliated Hospital of Xi’an Jiaotong University, No.157, Xiwu Road, Xi’an, Shaanxi, 710004, China. cor_renxiaoyong@126.com.

Haiqin Liu

Department of Otorhinolaryngology Head and Neck Surgery, The Second Affiliated Hospital of Xi’an Jiaotong University, No.157, Xiwu Road, Xi’an, Shaanxi, 710004, China. liuhaiqin_xjtu@163.com.