Neurology General | Physician's Weekly
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Neurology General

Randomized Controlled Trial of Fosmetpantotenate in Pantothenate Kinase–Associated Neurodegeneration

Jan 20, 2022

For a study, it was determined that there were currently no authorized therapies for pantothenate kinase-associated neurodegeneration (PKAN). The Fosmetpantotenate Replacement Therapy pivotal study in...

The Exquisite Motor Control Phenomenon in Tic Disorders and its Pathophysiological Implications

Jan 20, 2022

For a study, the phenotypic presentation of aberrant motor outputs, either as standalone events or in conjunction with additional clinical, typically neuropsychiatric, symptoms, was the unifying aspec...

A Systematic Review and Meta-Analysis of Evidence for Advanced Parkinson's Disease Patients

Jan 20, 2022

For a study, patients with severe Parkinson's disease (PD) commonly endured debilitating motor problems. Deep brain stimulation (DBS), levodopa-carbidopa intestinal gel (LCIG), and continuous subcutan...

The Parkinson's Long-COVID Spectrum: Parkinson's Disease and Post–COVID-19 Syndrome

Jan 20, 2022

For a study, the consequences of Severe Acute Respiratory Failure In multiple case series and observational studies, coronavirus 2 (SARS-CoV-2) infection was linked to increasing motor and non-motor s...

In Parkinson's Disease, Cerebella-Cortical Control of Tremor Rhythm and Amplitude

Jan 20, 2022

For a study, the basal ganglia and a cerebello-thalamocortical circuit were both involved in the pathogenesis of Parkinson's disease (PD) tremor. It was unknown how these circuits produced tremor rhyt...

Rapid Eye Movement Sleep Behaviour Disorder: Saccade, Pupil, and Blink Responses

Jan 20, 2022

For a study, patients with Parkinson's disease (PD) had abnormalities in saccade performance, pupil function, and blink rate. Isolated REM (rapid eye movement) Sleep Behavior Disorder (RBD) was a prec...

The Dystonic Signature of Primary Writing Tremor

Jan 20, 2022

For a study, it was determined that for decades it has been contested whether primary writing tremor is a kind of dystonic tremor, a variety of essential tremor, or a distinct entity. Researchers want...

Cannabidiol For The Treatment of Rapid Eye Movement Sleep Behaviour Disorder

Jan 20, 2022

For a study, it was determined that a typical non-motor characteristic of Parkinson's disease (PD) was REM sleep behavior disorder (RBD). Cannabidiol (CBD) was a non-psychoactive component of Cannabis...

Pallidum High-Frequency Oscillations

Jan 19, 2022

Abnormal rhythmic brain activity in the beta frequency band (13–35 Hz) is assumed to have a role in Parkinson's disease (PD); nevertheless, growing data suggests that changes in high-frequency range...

The interplay between Sleep and Gut Microbiota.

Jan 17, 2022

Sleep is a universal physiological need in all species and is essential for the maintenance and recovery of various physiological functions of the body. In late years, the gut microbiota (GM), a vast ...

Epileptic Seizure Detection Based on Bidirectional Gated Recurrent Unit Network.

Jan 17, 2022

Visual inspection of long-term electroencephalography (EEG) is a tedious task for physicians in neurology. Based on bidirectional gated recurrent unit (Bi-GRU) neural network, an automatic seizure det...

Improved access to rapid electroencephalography at a community hospital reduces inter-hospital transfers for suspected non-convulsive seizures.

Jan 17, 2022

Patients with suspected non-convulsive seizures are optimally evaluated with EEG. However, limited EEG infrastructure at community hospitals often necessitates transfer for long-term EEG monitoring (L...

Classical prescription Dachuanxiong Formula delays nitroglycerin-induced pain response in migraine mice through reducing endothelin-1 level and regulating fatty acid biosynthesis.

Jan 17, 2022

Dachuanxiong Formula (DCXF) is a classical Chinese medicine prescription and is composed of dried rhizomes from Ligusticum striatum DC. (Chuanxiong Rhizoma) and Gastrodia elata Bl. (Gastrodiae Rhizoma...

Education level is a strong determinant of cognitive function as measured by MoCA in people with chronic low back pain.

Jan 17, 2022

Over recent years there has been increasing clinical interest in the relationship between chronic pain and cognitive function. There are very few studies on individuals with low back pain (LBP) in the...

Increasing knowledge about recovery-related life domains among pregnant and parenting women in comprehensive substance use disorder treatment: The Art of Addiction Recovery Program.

Jan 17, 2022

Group treatments designed specifically for pregnant and parenting women with substance use disorders are lacking. This study provides a preliminary assessment of the Art of Addiction Recovery Program,...

Evaluation of the times of disability progression and related factors in patients with primary progressive multiple sclerosis from Argentina.

Jan 17, 2022

Background PPMS (primary progressive multiple sclerosis) patients represent less than 10% of MS patients in Argentina, men and women were similarly affected and most of them had a severe functional im...

Quality of life of patients with multiple sclerosis and neuromyelitis optica spectrum disorders: Cross-sectional and longitudinal analysis.

Jan 17, 2022

Multiple sclerosis (MS) and aquaporin-4 antibody-positive neuromyelitis optica spectrum disorders (NMOSD), which have different pathogenic mechanisms, both negatively affect patients during their life...

Transient Global Amnesia.

Jan 17, 2022

Transient global amnesia (TGA) is a clinical syndrome characterized by anterograde amnesia, mild retrograde amnesia, and confusion up to 24 hours. Most commonly seen in patients older than 50 years, T...

Proteomic Investigation in Plasma from Women with Fibromyalgia in Response to a 15-wk Resistance Exercise Intervention.

Jan 17, 2022

Fibromyalgia (FM) is a complex pain condition, and exercise is considered the first option of treatment. Few studies have examined the effect of exercise on molecular mechanisms in FM. The aim of this...

Midurethral Sling Removal or Revision in Women with Chronic Pain.

Jan 17, 2022

The objectives of this study are (1) to estimate the incidence of midurethral sling revision/removal in women with preexisting pain diagnoses versus those without these diagnoses and (2) to describe a...