Jul 02, 2020

Restoration of coronary blood flow after a heart attack can cause reperfusion injury potentially leading to impaired cardiac function, adverse tissue remodeling and heart failure. Iron is an essential...

Jul 02, 2020

Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection. Mortality rates are high, exceeding 50% in patients with septic shock. The sepsis severit...

Jul 02, 2020

Trefoil factor 3 (TFF3) is a small peptide secreted mainly by goblet cells in the gut, where it plays a key role in gastrointestinal defence and repair. Plasma TFF3 has been reported as a biomarker of...

Jul 02, 2020

Coronavirus disease 2019 (COVID-19) is a life-threatening respiratory illness caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Its clinical presentation can vary from ...

Jul 02, 2020

The thrombopoietin receptor agonist romiplostim (RP) is a therapeutic agent for immune thrombocytopenia that can achieve complete survival in mice exposed to a lethal dose of ionizing radiation. The ...

Jul 02, 2020

To determine the relationship between neurovascular coupling (NVC), vision and sensory performance in Special Operations Forces (SOF) combat soldiers with and without concussion history. We studied 6...

Jul 02, 2020

The widespread use of opioids for the treatment of moderate or severe acute and chronic pain has become a public health problem due to the physical and psychological dependence and tolerance they prod...

Jul 02, 2020

His bundle pacing (HBP) and left bundle pacing (LBP) are emerging as novel delivery methods for cardiac resynchronisation therapy (CRT) in heart failure patients with left bundle branch block (LBBB). ...

Jul 02, 2020

Digoxin reduces the risk of heart failure hospitalization but has no effect on mortality in patients with heart failure without atrial fibrillation in the randomized controlled trial setting. Observat...

Jul 02, 2020

Although exercise training (ET) has been shown to improve both physical function and health-related quality of life (HRQOL) in older patients with heart failure and preserved ejection fraction (HFpEF)...

Jun 29, 2020

The activation of NLRP3 inflammasome is closely related to ischemic brain injury and inhibition of NLRP3 inflammasome activation may be a new therapeutic strategy for ischemic stroke. Our previous stu...

Jun 29, 2020

We aimed to compare the effectiveness of single- vs multiple-strain probiotics in a network meta-analysis of randomized trials.We searched MEDLINE, EMBASE, Science Citation Index Expanded, CINAHL, Sco...

Jun 29, 2020

Shenfu injection (SFI) is a well-known Chinese herbal medicine widely used in the treatment of septic shock in China.The aims of this study are to investigate the protective effects of SFI on sepsis-i...

Jun 29, 2020

The effect of body-mass index (BMI) on the risk of infectious diseases admissions and mortality is unclear and is difficult to study given risks of confounding variables.We used genome-wide associatio...

Jun 29, 2020

Coccidioidal meningitis is a life-threatening condition and a diagnostic challenge in cases of chronic meningitis. It is associated to severe complications, like basal arachnoiditis, hydrocephalus, an...

Jun 29, 2020

COVID-19 carries a high risk of severe disease course, particularly in patients with comorbidities. Therapy of severe COVID-19 infection has relied on supportive intensive care measures. More specific...

Jun 29, 2020

Background Ischemic heart disease, particularly inferior wall myocardial infarction (IWMI), is a significant issue in cardiac health. It can further add up to the morbidity and mortality when it is as...

Jun 29, 2020

On March 13, 2020, the United States declared a national emergency in response to the coronavirus disease 2019 (COVID-19) pandemic. Subsequently, states enacted stay-at-home orders to slow the spread ...

Jun 29, 2020

In heart attack, FSTL-1 is actively secreted by cardiomyocytes, accelerates growth of heart myofibrils and stimulates of vascular endothelial growth factor expression. The aim of this work was to inve...

Jun 29, 2020

40%-50% of this septic arthritis occurs in the knee, despite rapid medical surgical treatment, 24%-50% will have a poor clinical outcome. It is not clear which debridement technique, by arthrotomy or ...