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Endocrinology General

Adult Diabetes and Hyperglycemia in The Americas, 1990-2019

Sep 20, 2022

For a study, researchers sought to characterize the prevalence of type 1 and type 2 diabetes (T1D, T2D) and hyperglycemia across the Americas from 1990 to 2019. Using projections from Global Burden of...

Preventing Major Cardiovascular Diseases in Individuals with and Without Type 2 Diabetes by Lowering Blood Pressure

Sep 20, 2022

The study examines the relationship between systolic blood pressure and cardiovascular risk in adults with and without type 2 diabetes. Researchers did a meta-analysis of randomized controlled trials ...

Primary Aldosteronism and Renin Suppression Help to Improve Left Ventricular Function

Sep 15, 2022

Cardiovascular events are more likely to occur in people with primary aldosteronism (PA). The usual assessment using LV ejection fraction (LVEF), however, has not demonstrated that therapy of PA impro...

The Reproductive Outcome of Women with HH in IVF

Aug 17, 2022

For a study, researchers sought to assess the reproductive success of hypogonadotropic hypogonadism (HH) patients who underwent in vitro fertilization and embryo transfer (IVF-ET). From 2010 to 201...

NR0B1 Novel Truncating Variant With X-Linked Late-Onset AHC & Hypogonadotropic Hypogonadism

Aug 17, 2022

The orphan nuclear receptor that is encoded by the nuclear receptor subfamily 0 group B member 1 gene (NR0B1) is essential for the growth and control of the adrenal gland and hypothalamic-pituitary-go...

MAMLD1 Variant in Microphallus & Hypospadias Infant With Hormonal Pattern

Aug 17, 2022

One identified gene connected to the development of distinct sexes is MAMLD1 (X chromosome). It appears to be involved in the development of fetal sex and adult reproductive function, including testos...

Adult-onset Hypogonadism (AOH) and Phthalate Metabolites

Aug 16, 2022

Males >40 years frequently develop adult-onset hypogonadism (AOH), a condition that is highly correlated with age-related comorbidities. Phthalates are substances having endocrine-disrupting proper...

FSH and Bone: Males with Central Vs. Primary Hypogonadism

Aug 16, 2022

Follicle-stimulating hormone (FSH) was shown to have a direct impact on bone metabolism in experimental investigations, but the results of human studies, which were primarily done in females, were unr...

Medications for Puberty Induction and Maintenance in Hypogonadism Adolescents

Aug 12, 2022

Inducing puberty in hypogonadal patients allows for the accumulation of healthy bone density, a normal ultimate adult height, and increases reproductive potential. However, access to and reliable supp...

Lifestyle Intervention Aids Older Adults With Diabetes

Aug 05, 2022

Clinicians should implement lifestyle intervention as a primary therapy for older adults with diabetes, which could complement medical therapy and improve QOL. “Although lifelong intervention...

Lipid Variability & Risk of Microvascular Complications in ACCORD Trial

Jul 29, 2022

For a study, researchers sought to look at the impact of lipid inconstancy on the gamble of diabetic microvascular results among type 2 diabetes mellitus patients. They surveyed the relationship betwe...

Type 2 diabetes Impact on a Disintegrin and Metalloprotease 10

Jul 29, 2022

For a study, researchers sought to understand that as a sort 1 transmembrane protein, a disintegrin and metalloprotease 10 (ADAM10) is liable for the cleavage of an assortment of cell surface particle...

Early Metabolomic Markers Can Predict Gestational Diabetes

Jul 25, 2022

Changes in pregnant women's blood were found in metabolites from early to mid-pregnancy that were linked with the risk for gestational diabetes in later pregnancy. “Gestational diabetes is ty...

Efficiency of ATA Dialyser to Polysulfone Dialyser Membrane in Haemodialysis

Jul 06, 2022

For a study, researchers sought to compare small, intermediate, and large-middle molecule clearance and the expression of inflammatory markers in long-hour hemodialysis patients using Solacea-190H (as...

Comorbidity Did Not Affect Dialysis Modality Selection in Individuals with End-Stage Renal Disease

Jul 06, 2022

The proportion of home dialysis patients has declined in recent years. Furthermore, the usage of home dialysis varies greatly amongst centers. Therefore, it was unclear if it was due to comorbidity di...

Peritoneal Dialysis Patients' Self-Assessment Sheet Submission Rate Predicts Technique Survival

Jul 06, 2022

Because peritoneal dialysis (PD) is mostly performed at home, patients play an important role in avoiding PD-related complications such as peritonitis and fluid overload. Therefore, in their daily cli...

Circulating C-Peptide Levels in Children and Young People

Jul 06, 2022

C-peptide levels decrease in type 1 diabetes, while many long-term patients maintain detectable amounts. Histological examinations demonstrated the presence of β-cells after the beginning of type 1 d...

SARS-CoV-2 Infects Human Pancreatic Islets in Both Indirect & Direct Ways

Jul 06, 2022

Recent research suggested that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection might cause metabolic distress, resulting in hyperglycemia in coronavirus disease (COVID-19) patie...

HIF-2 Protects Mitochondrial Activity and Glucose Sensing in Obese Compensating -Cells

Jul 06, 2022

Obesity causes mitochondrial damage and β-cell dysfunction due to increased mitochondrial metabolism and the buildup of oxidative stress. β-cells, in particular, express antioxidant enzymes at low q...

PYY-Induced Nausea is Inhibited by GIPR Agonism

Jul 05, 2022

The generation of nausea and emesis is a significant obstacle to optimizing the weight loss profile of obesity drugs; hence, discovering strategies that increase tolerability might result in further t...