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Laser Surgery

Comparison of early changes in tear film protein profiles after small incision lenticule extraction (SMILE) and femtosecond LASIK (FS-LASIK) surgery.

Feb 19, 2024

Small incision lenticule extraction (SMILE) and femtosecond laser-assisted in situ keratomileusis (LASIK) are widely used surgical methods to correct myopia with comparable efficacy, predictability, a...

The role of transforming growth factor beta in myopia development.

Feb 12, 2024

Myopia is widely recognized as an epidemic. Studies have found a link between Transforming Growth Factor-beta (TGF-β) and myopia, but the specific molecular mechanisms are not fully understood. In th...

A novel variant of DNM1L expanding the clinical phenotypic spectrum: a case report and literature review.

Feb 12, 2024

Mitochondrial diseases are heterogeneous in terms of clinical manifestations and genetic characteristics. The dynamin 1-like gene (DNM1L) encodes dynamin-related protein 1 (DRP1), a member of the GTPa...

Geometric transformation adaptive optics (GTAO) for volumetric deep brain imaging through gradient-index lenses.

Feb 05, 2024

The advance of genetic function indicators has enabled the observation of neuronal activities at single-cell resolutions. A major challenge for the applications on mammalian brains is the limited opti...

Extending the Scope of Conceptual Density Functional Theory with Second Order Analytical Methodologies.

Feb 05, 2024

In the context of the growing impact of conceptual density functional theory (DFT) as one of the most successful chemical reactivity theories, response functions up to second order have now been widel...

Open Fundus Photograph Dataset with Pathologic Myopia Recognition and Anatomical Structure Annotation.

Jan 22, 2024

Pathologic myopia (PM) is a common blinding retinal degeneration suffered by highly myopic population. Early screening of this condition can reduce the damage caused by the associated fundus lesions a...

Relationship between dynamic visual acuity and static visual acuity, refractive error, and binocular vision in elite soccer players.

Jan 22, 2024

In many sports, dynamic visual acuity is used. In order to improve dynamic visual acuity, it is important to understand the aspects of the visual system that can cause compromise.To investigate the pa...

Outcome of combined cataract surgery and iris prosthesis implantation in iris melanoma patients previously treated with iridocyclectomy: A national retrospective non-comparative case series.

Jan 15, 2024

To examine complications, visual outcomes, photic patient-reported symptoms, corneal morphology, IOL tilt, and intraocular pressure after implantation of an intraocular lens (IOL) and iris prosthesis ...

Spherical equivalent pre- and post-implantable collamer lens implantation in patients with myopia, hyperopia, and stable keratoconus.

Jan 01, 2024

Refractive errors are common in Saudi Arabia and keratorefractive surgeries are usually done to correct them. However, not all patients are fit and complications postoperatively are a concern. Implant...

RNA-Sequencing Analysis Reveals the Role of Mitochondrial Energy Metabolism Alterations and Immune Cell Activation in Form-Deprivation and Lens-Induced Myopia in Mice.

Dec 25, 2023

Myopia is a substantial global public health concern primarily linked to the elongation of the axial length of the eyeball. While numerous animal models have been employed to investigate myopia, the s...

A Corneal Biomechanical Study Measured with a Scheimpflug Dynamic Analyser in Soft Contact Lens Wearers.

Dec 25, 2023

The aim of this study was to evaluate the biomechanical changes in the cornea after wearing soft contact lenses (CLs) in healthy myopic patients measured with a Corvis ST (CST, Oculus Optikgeräte Gmb...

Targeting scleral remodeling and myopia development in form deprivation myopia through inhibition of EFEMP1 expression.

Dec 18, 2023

The role of extracellular matrix (ECM) remodeling in the axial elongation associated with myopia has not been fully elucidated, although it is considered a significant factor. EFEMP1, a regulator of E...

Bayesian posterior density estimation reveals degeneracy in three-dimensional multiple emitter localization.

Dec 18, 2023

Single-molecule localization microscopy requires sparse activation of emitters to circumvent the diffraction limit. In densely labeled or thick samples, overlap of emitter images is inevitable. Single...

Effect of myopia-control lenses on central and peripheral visual performance in myopic children.

Dec 11, 2023

To evaluate the short-term effects of three myopia-control lenses, which impose peripheral myopic defocus while providing clear central vision, on central and peripheral visual performance in myopic c...

High myopia is protective against diabetic retinopathy in the participants of the National Health and Nutrition Examination Survey.

Nov 20, 2023

To investigate the association of subjects with refractive error and diabetic retinopathy (DR) in the United States comparing results between different race groups.All data were derived from National ...

Exploration of the pathophysiology of high myopia via proteomic profiling of human corneal stromal lenticules.

Nov 20, 2023

This study aimed to investigate the underlying pathophysiology of high myopia by analyzing the proteome of human corneal stromal lenticule samples obtained through small incision lenticule extraction ...

Intraocular cetuximab: Safety and effect on axial elongation in young Guinea pigs with lens-induced myopization.

Nov 13, 2023

This study aimed to examine the intraocular tolerability of the epidermal growth factor receptor antibody cetuximab, when applied intravitreally, and its effect on axial elongation. Guinea pigs aged 2...

The corneal biomechanical differences after wearing orthokeratology lenses and multifocal soft lenses in children: A self-control study.

Nov 13, 2023

To compare the changes in corneal biomechanics after orthokeratology (OK) lens and Defocus Incorporated Soft Contact (DISC) lens treatment.Of 28 myopic children were recruited, with one eye wearing OK...

Six-year cumulative treatment effect and treatment efficacy of a dual focus myopia control contact lens.

Oct 30, 2023

Accumulated axial growth observed during a 6-year clinical trial of a dual focus myopia control contact lens was used to explore different approaches to assess treatment efficacy.Axial length measurem...

Association of macular outward scleral height with axial length, macular choroidal thickness and morphologic characteristics of the optic disc in Chinese adults.

Oct 30, 2023

To identify the relationship of macular outward scleral height (MOSH) with axial length (AL), macular choroidal thickness (ChT), peripapillary atrophy (PPA), and optic disc tilt in Chinese adults.In t...

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