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OB/GYN General

Seroprevalence of rubella virus among pregnant women: A 4-year registered based study from Family medicine and Obstetric clinics in Saudi Arabia.

Mar 22, 2021

This study aimed to determine rubella virus infectivity and immune status in pregnant females visited the family medicine and obstetrics clinics at a large hospital in Saudi Arabia, and to identify th...

Identification of MEG8/miR-378d/SOBP axis as a novel regulatory network and associated with immune infiltrates in ovarian carcinoma by integrated bioinformatics analysis.

Mar 22, 2021

To investigate the potential molecular mechanism of ovarian cancer (OC) evolution and immunological correlation using the integrated bioinformatics analysis.Data from the Gene Expression Omnibus was u...

Impact of health-related quality of life (HRQoL) on short-term mortality in patients with recurrent ovarian, fallopian or peritoneal carcinoma (the NOGGO-AGO QoL Prognosis-Score-Study): results of a meta-analysis in 2209 patients.

Mar 22, 2021

Recurrent ovarian cancer is an incurable disease with variable but poor prognosis. Health-related quality of life (HRQoL) is a patient-reported outcome measure generally applied to measure effects of ...

Galanin and glypican-4 levels depending on metabolic and cardiovascular risk factors in patients with polycystic ovary syndrome.

Mar 22, 2021

Galanin is a neuropeptide which has effects not only on metabolic syndrome but also on reproduction. Glypican-4 is an adipokine associated with insulin sensitivity by interacting directly with the ins...

Diagnosis and treatment of diaphragmatic endometriosis: results of an international patient survey.

Mar 22, 2021

To quantify the delays associated with the diagnosis and treatment of diaphragmatic endometriosis (DE), and to evaluate patient-reported postoperative outcomes.An anonymous survey was designed to coll...

Use of fertility drugs and risk of malignant melanoma: results from a large Danish population-based cohort study.

Mar 22, 2021

Fertility drugs have not definitively been linked to malignant melanoma. By use of data from a large nationwide cohort of women aged 20.0 to 45.0 years and living in Denmark between January 1, 1995 an...

Immune analysis of lymph nodes in relation to the presence or absence of tumor infiltrating lymphocytes in triple-negative breast cancer.

Mar 22, 2021

Triple-negative breast cancer (TNBC) is a subtype of breast cancer with unmet medical needs. Several studies have proved that high levels of tumor infiltrating lymphocytes (TILs) at diagnosis of TNBC ...

Therapy response and prognosis of patients with early breast cancer with low positivity for hormone receptors - An analysis of 2765 patients from neoadjuvant clinical trials.

Mar 22, 2021

To evaluate HER2-negative breast cancer (BC) with a low hormone receptor (HR) expression, with regard to pathological complete response (pCR) and survival, in comparison to triple-negative BC (TNBC) a...

EXPRESS: Does Non-Implanted Electrical Stimulation Reduce Post-Stroke Urinary or Fecal Incontinence? A Systematic Review with Meta-Analysis.

Mar 18, 2021

Urinary and fecal incontinence are disabling impairments after stroke that can be clinically managed with electrical stimulation.The purpose of this systematic review was to determine the effectivenes...

A comparison of faecal incontinence scoring systems.

Mar 18, 2021

Questionnaires designed to score the severity of faecal incontinence (FI) are widely used to provide an evaluation of symptoms across settings, studies and time. The Pelvic Floor Disorders Consortium ...

Successful laparoscopy-assisted repair of a rectovaginal fistula after low anterior resection for rectal cancer: a report of two cases.

Mar 18, 2021

Rectovaginal fistula (RVF) after low anterior resection for rectal cancer is troublesome and refractory. Although various surgical procedures have been previously described, no definitive procedure ha...

Postpartum depression and anxiety: a community-based study on risk factors before, during and after pregnancy.

Mar 18, 2021

Depression and anxiety occur frequently postpartum, calling for early detection and treatment. Evidence on risk factors may support early detection, but is inconclusive. Our aim was to identify risk f...

Poly (ADP-ribose) polymerase (PARP) as target for the treatment of epithelial ovarian cancer: what to know.

Mar 18, 2021

Poly (ADP-ribose) polymerase (PARP) inhibitors are being developed in maintenance and recurrence treatment settings of epithelial ovarian cancers (EOCs) with BRCA 1-2 genes mutation. PARP inhibitors a...

The results of multigene panel sequencing in Slovak HBOC families.

Mar 18, 2021

Hereditary breast and ovarian cancer (HBOC) is primarily associated with mutations in the BRCA1/2 genes. However, causal variants in other high, moderate, and low penetrance genes proportionally incre...

Non-contrast MRI can accurately characterize adnexal masses: a retrospective study.

Mar 18, 2021

To determine the accuracy of interpretation of a non-contrast MRI protocol in characterizing adnexal masses.Two hundred ninety-one patients (350 adnexal masses) who underwent gynecological MRI at our ...

Fennel (Foeniculum vulgare Miller) for the management of menopausal women's health: A systematic review and meta-analysis.

Mar 18, 2021

This review aimed to evaluate the current evidence on the effectiveness and safety of fennel (Foeniculum vulgare Miller) for managing menopausal women's health. Fourteen databases were searched. We in...

E3 ubiquitin ligase TRIM24 deficiency promotes NLRP3/Caspase-1/IL-1β-mediated pyroptosis in endometriosis.

Mar 18, 2021

Endometriosis is an inflammation-dependent disease which shares similarities with malignant tumors including attachment and infiltration. Tripartite motif containing 24 (TRIM24) has been illustrated i...

How did women with breast cancer experience the first wave of the COVID-19 pandemic? A qualitative study.

Mar 18, 2021

The ongoing COVID-19 global pandemic is a stressful experience that is particularly likely to negatively affect cancer patients. The goal of this qualitative study was to explore how breast cancer pat...

Factors Influencing Mammography Uptake Following a Screening Intervention among Asian American Women: A Systematic Review.

Mar 18, 2021

Asian American women, both immigrant and US-born, are known to have low mammography screening rates. To reduce health disparities and address community health needs, we undertook a systematic review t...

Cross-Resistance and the Mechanisms of Cephalosporin-Resistant Bacteria in Urinary Tract Infections Isolated in Indonesia.

Mar 15, 2021

Urinary tract infection (UTI) by antibiotic-resistant strains has become increasingly problematic, with trends that differ from country to country. This study examined cross-resistance and the mechani...

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