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OB/GYN General

CircRAB11FIP1 promoted autophagy flux of ovarian cancer through DSC1 and miR-129.

Mar 01, 2021

At present, no systematic and in-depth study is available on the function and potential mechanisms of circular RNA in autophagy. This study aimed to screen the expression profiles of circRNA, miRNA, a...

Incidence of venous thromboembolism after standard treatment in patients with epithelial ovarian cancer in Korea.

Mar 01, 2021

Venous thromboembolism (VTE) is a hospital-associated severe complication that may adversely affect patient prognosis. In this study, we evaluated the incidence of VTE and its risk factors in patients...

Predictors of hypertensive disorders in pregnancy in women with and without polycystic ovary syndrome: Australian Longitudinal Study of Women's Health.

Mar 01, 2021

A higher risk of hypertensive disorders in pregnancy (HDP) is frequently reported in women with polycystic ovary syndrome (PCOS). These women, however, have a higher risk profile for HDP compared to w...

Glutathionylation-dependent proteasomal degradation of wide-spectrum mutant p53 proteins by engineered zeolitic imidazolate framework-8.

Mar 01, 2021

Point mutations within the DNA-binding domain of the TP53 gene occur in a significant percentage of human cancer, leading to cellular accumulation of highly stabilized mutant p53 proteins (mutp53) wit...

Beta-blockers in early-stage breast cancer: a systematic review and meta-analysis.

Mar 01, 2021

Preclinical and retrospective studies suggest that beta-blockers are active against breast cancer. We carried out a systematic review and meta-analysis to assess the impact of beta-blockers on the out...

Follistatin-like 1 deficiency impairs T cell development to promote lung metastasis of triple negative breast cancer.

Mar 01, 2021

Our study aims to detect the underlying mechanism of the suppressive effect of Follistatin-like 1 (FSTL1) on lung metastasis of triple negative breast cancer (TNBC). We found that FSTL1 had no effect ...

Point-of-care ultrasound in obstetrics and gynecology.

Mar 01, 2021

The rapid technical development and portability of ultrasound systems over recent years has had a profound impact on the area of point-of-care-ultrasound (POCUS), both in general medicine and in obste...

The Preparing Residents for International Medical Experiences (PRIME) Simulation Workshop: Equipping Surgery and Anesthesia Trainees for International Rotations.

Mar 01, 2021

Although global health training expands clinical and sociocultural expertise for graduate medical trainees and is increasingly in demand, evidence-based courses are limited. To improve self-assessed c...

Reliability and validity of Midwifery - Obstetrics Collaboration (MOC) scale: A tool to improve collaborative practice.

Mar 01, 2021

In recent decades, there has been a call to foster effective collaborative models of practice between midwives and obstetricians/gynecologists (OB/GYNs) in the United States in order to improve clinic...

Updated Guidance on Fertility Preservation & Post-Treatment Pregnancy in Patients With Post-Pubertal Cancer

Feb 22, 2021

With long-term survivorship increasingly achievable among patients with cancer, many in this population face the outcomes of treatment-related late effects, explain Richard Anderson, MD, PhD, Matteo L...

Oral GnRH Antagonist Relugolix Reduces Heavy Menstrual Bleeding

Feb 19, 2021

Combo treatment not linked to reduced bone mineral density in LIBERTY trials Combination therapy with the oral gonadotropin-releasing hormone-receptor (GnRH) antagonist relugolix was associated with ...

Covid-19: Updated Guidance on Vaccines, Masks, and... Mammograms?

Feb 16, 2021

Public health organizations release new recommendations as pandemic rages on The CDC and other public health entities recently issued a host of new Covid-19 guidance, with recommendations covering to...

Covid-19:Moms Pass SARS-CoV-2 Antibodies—But Rarely Infection—to Newborns

Feb 02, 2021

Transplacental transfer of SARS-CoV-2 antibodies documented in seropositive pregnant women Maternally derived SARS-CoV-2 specific antibodies may protect newborns from coronavirus, according to result...

Empathy, The Best Medicine? How Doctors can Help Patients Remember More Information and Make Better-Informed Decisions

Jan 29, 2021

The expression “It shouldn’t have to happen to you to matter to you” has been making the rounds on social media platforms lately. In my opinion, it’s a great way to define empathy, our ability...

FDA to Hold Public Workshop on Including Pregnant Women in Clinical Trials

Jan 14, 2021

Feb. 2-3 meeting will focus on scientific and ethical issues surrounding inclusion WASHINGTON — The FDA intends to hold a virtual public workshop on Feb. 2 and 3 to discuss the scientific and e...

Examining the Risk of VTE in Ovarian Cancer

Dec 15, 2020

Published research has shown that women with ovarian cancer have among the highest rates of venous thromboembolisms (VTEs) of all patients with cancer. “An estimated 5% to 25% of patients with ovari...

Prescribed Medical Cannabis in Women With Gynecologic Malignancies

Dec 14, 2020

Although cannabis remains illegal in many parts of the United States, 33 states have approved medical cannabis programs as of March 2020. “With the likely expansion of medical cannabis across the US...

Amenorrhea & Bone Mineral Density in Women With HIV

Nov 06, 2020

Although previous studies indicate that HIV is a risk factor for missed menstrual periods, or amenorrhea, the downstream effects of amenorrhea and its associated hormonal dysregulation in these women ...

Waves of Postpartum Depression Can Ebb and Flow for Years

Nov 03, 2020

Experts advise pediatricians to be alert for signs of depressive symptomatology Postpartum depression is not simply something that happens shortly after birth and then goes away — a new, longit...

Survival After Minimally Invasive vs Open Radical Hysterectomy for Early-Stage Cervical Cancer

Oct 13, 2020

Previous research has shown that women with early-stage cervical cancer who undergo radical hysterectomy are usually cured, with some reports demonstrating 5-year disease-free survival rates that exce...

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