Ovarian Cancer
Dec 17, 2020
AdCD40L is a replication-deficient virus carrying the gene for CD40 ligand which has previously been evaluated in patients with urothelial cancer and malignant melanoma. Herein, we present the results...
Dec 15, 2020
Published research has shown that women with ovarian cancer have among the highest rates of venous thromboembolisms (VTEs) of all patients with cancer. “An estimated 5% to 25% of patients with ovari...
Dec 14, 2020
Although cannabis remains illegal in many parts of the United States, 33 states have approved medical cannabis programs as of March 2020. “With the likely expansion of medical cannabis across the US...
Dec 14, 2020
Delivery of therapeutic small interfering RNA (siRNA) via functionalized nanoparticles holds great promise for cancer therapy. However, developing a safe and efficient delivery carrier of siRNA is a c...
Dec 14, 2020
B-cell CLL/lymphoma 7 protein family member C (BCL7C) located at chromosome 16p11.2 shares partial sequence homology with the other two family members, BCL7A and BCL7B. Its role in cancer remains comp...
Dec 14, 2020
The growth and spread of malignant tumors such as ovarian carcinomas are governed in part by complex interconnected-signaling cascades occurring between stromal and tumor cells. These reciprocal cross...
Dec 10, 2020
Although ovarian cancer is the leading cause of death from gynecological malignancies, there are still some issues that hamper accurate interpretation of the complexity of cellular and molecular event...
Dec 10, 2020
Despite high-grade serous ovarian cancer (HGSOC) being the most common and lethal gynecological cancer in women, the early etiological events driving disease development remain largely unknown. Emergi...
Dec 10, 2020
This study aimed to investigate the effects of multiwalled carbon nanotubes (MWCNTs) on cytotoxicity and tumor metastasis in ovarian cancer cells, and further explored its mechanism.MWCNTs significant...
Dec 07, 2020
The current study was undertaken to examine the anticancer potential of davanone against human ovarian cancer cells along with evaluating its effects on cell apoptosis, PI3K/AKT/MAPK signaling pathway...
Dec 07, 2020
The medical and surgical treatment strategies for women with epithelial ovarian cancer continue to evolve. In the past several years, there has been significant progress backed by landmark clinical tr...
Dec 07, 2020
Ovarian cancer is one of three major malignancies of the female reproductive system. DNA methylation (MET) is closely related to ovarian cancer occurrence and development, and as such, elucidation of ...
Dec 03, 2020
The ability of tumor cells to sustain continuous proliferation is one of the major characteristics of cancer. The activation of oncogenes and the mutation or inactivation of tumor suppressor genes ens...
Dec 03, 2020
This study aimed to investigate the predictive value of laparoscopy for the prediction of optimal cytoreduction and prognosis of epithelial ovarian cancer (EOC) in a Chinese population.This study enro...
Dec 03, 2020
The objective of this study is to explore the role of miR-210 in the growth of ovarian cancer cells and the correlation with radiotherapy and to elucidate underlying molecular mechanisms.Human ovarian...
Nov 30, 2020
This study was aimed at investigating the effects of long noncoding RNA (lncRNA) LINC02323 in ovarian cancer and its possible mechanism.Microarray analysis and QPCR were utilized to identify lncRNA L...
Nov 30, 2020
Programmed cell death ligand 1 (PD-L1), inducing T cells exhaustion to facilitate immune escape of tumor cells, is up-regulated by interleukin 6 (IL-6) in T-Cell Lymphoma and ovarian cancer. The purpo...
Nov 30, 2020
Compare survival between patients with advanced epithelial ovarian cancer (EOC) undergoing interval debulking surgery (IDS), comparing robotic-assisted (R-IDS) and open (O-IDS) approach. Secondarily, ...
Nov 26, 2020
SMARCA4 and EZH2 are two functional key players of their respective antagonizing chromatin remodeling complexes SWI/SNF and PRC2. EZH2 inhibitory drugs may abrogate pro-oncogenic features of PRC2 and ...
Nov 26, 2020
Genotype-first approach allows to systematically identify carriers of pathogenic variants in BRCA1/2 genes conferring a high risk of familial breast and ovarian cancer. Participants of the Estonian bi...