Sep 14, 2022

For a study, researchers sought to assess the association between insurance status and clinical and financial outcomes and financial toxicity (FT) risk among inpatients receiving gynecologic cancer re...

Sep 12, 2022

For a study, researchers sought to comprehend the effects that treatment-related financial burden has on gynecologic cancer patients and to pinpoint areas that may be targeted for treatments to lessen...

Sep 12, 2022

With stage, I to IV uterine carcinosarcoma patients are treated with surgery followed by adjuvant chemotherapy alone, radiation therapy alone, or a combination of chemotherapy and radiation therapy. F...

Jun 13, 2022

Patients undergoing surgery for gynecologic cancer, particularly those without insurance, experience a significant risk for financial toxicity, according to findings published in Gynecologic Oncology....

Jun 07, 2022

The linguistic origin of pyroptosis is Greek—pyro meaning fire and ptosis meaning falling or dropped. In science, the term pyroptosis appropriately refers to a highly inflammatory pathway toward reg...

Apr 28, 2022

Molecular classification served as a significant marker of survival following endometrial cancer (EC) recurrence, with patterns of recurrence that varied based on molecular subgroups, according to fin...

Apr 27, 2022

Black women experience higher mortality from endometrial cancer (EC) than White women, according to published data, and potential reasons for this disparity include increased rates of obesity and more...

Dec 15, 2021

Long-term use of tamoxifen is associated with an increased risk for the development of uterine cancer. New research shows that tamoxifen directly activates a signaling pathway (PIK3) that is a well-kn...

Dec 14, 2021

The phase 3 RxPONDER trial evaluated the benefit of adjuvant chemotherapy followed by endocrine therapy in women with HR-positive, HER2-negative, early-stage breast cancer and 1–3 positive nodes. Up...

Dec 14, 2021

There remains an “urgent need” for better therapies, as well as earlier diagnosis and earlier identification of recurrences, in endometrial cancer, according to the authors of a study published in...

Sep 13, 2021

Circular RNAs (circRNAs) are gradually reported to be implicated in the development of malignant tumors, including ovarian cancer (OC). This paper intended to explore the function and action mechanism...

Sep 13, 2021

Gynecologic cancers seriously threaten women's life and health. This study aims to assess the long-term trends of mortality from the three major gynecologic cancers in China and to examine the age-, p...

Sep 13, 2021

BRCA1/2 mutant tumor cells display an elevated mutation burden, the etiology of which remains unclear. Here, we report that these cells accumulate ssDNA gaps and spontaneous mutations during unperturb...

Aug 30, 2021

The effect of serum lipids on ovarian cancer is controversial. We conducted this study to evaluate the prognostic value of preoperative plasma lipid profile in patients with ovarian cancer.The medical...

Aug 30, 2021

To clarify the clinical as well as pathological outcomes in Japanese women with germline pathogenic BRCA1/2 variants who underwent risk-reducing salpingo-oophorectomy (RRSO).This prospective study exa...

Aug 30, 2021

Ovarian cancer represents the third gynecological cancer in frequency in Argentina. There is a lack of information on this pathology in our country regarding the treatment and evolution of patients wh...

Aug 19, 2021

The present study aimed to explore the expressions of long noncoding RNA (lncRNA) p53 upregulated regulator of p53 levels (PURPL) in different ovarian tissues, and to evaluate the significance of dis...

Aug 19, 2021

Nucleic acids are well-established biomarkers of cancer with immense value in diagnostics and basic research. However, strategies to monitor these species in tissue can be challenging due to the need ...

Aug 19, 2021

Despite wide use of anti-vascular endothelial growth factor (VEGF) therapy for many solid cancers, most individuals become resistant to this therapy, leading to disease progression. Therefore, new bio...

Aug 05, 2021

Chemotherapy for end-of-life ovarian cancer patients is a complex and delicate problem. We evaluated whether active palliative chemotherapy is beneficial for such patients using inflammatory parameter...