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Ovarian Cancer

Intention matters: Success rate of bilateral salpingo-oophorectomy at the time of vaginal hysterectomy for pelvic organ prolapse.

Feb 13, 2023

The objective of this study was to determine the incidence of successful bilateral salpingo-oophorectomy at the time of vaginal hysterectomy for pelvic organ prolapse and to evaluate associated factor...

Therapeutic effect of haploidentical peripheral blood stem cell treatment on relapsed/refractory ovarian cancer.

Feb 06, 2023

The traditional immunotherapy is limited on relapsed/refractory metastatic ovarian cancer because tumors cause immunosuppression. Since new therapeutic strategies to improve clinical outcomes for pati...

Development and verification of a 7-lncRNA prognostic model based on tumor immunity for patients with ovarian cancer.

Feb 06, 2023

Both immune-reaction and lncRNAs play significant roles in the proliferation, invasion, and metastasis of ovarian cancer (OC). In this study, we aimed to construct an immune-related lncRNA risk model ...

[The expression and significance of protease activated receptor 2 in ovarian epithelial carcinoma].

Jan 30, 2023

To investigate the expression and significance of protease activated receptor 2 (PAR2) in ovarian epithelial carcinoma. PAR2 mRNA expression levels in 410 cases of epithelial ovarian carcinoma and 8...

The epigenetic factor CHD4 contributes to metastasis by regulating the EZH2/β-catenin axis and acts as a therapeutic target in ovarian cancer.

Jan 23, 2023

The overall survival rate of patients with advanced ovarian cancer (OC) has remained static for several decades. Advanced ovarian cancer is known for its poor prognosis due to extensive metastasis. Ep...

High visceral fat-to-muscle ratio is an independent factor that predicts worse overall survival in patients with primary epithelial ovarian, fallopian tube, and peritoneal cancer.

Jan 23, 2023

The intra-abdominal cavity, surrounded by adipocytes, is the main metastatic site of epithelial ovarian, fallopian tube, and peritoneal cancer. Epidemiological and molecular studies have demonstrated ...

A comparison of synoptic reports and dictated reports to enhance and standardize surgical documentation and quality of care in epithelial ovarian cancer.

Jan 16, 2023

The purpose of this study is to assess the degree to which synoptic reports (SRs) and dictated reports (DRs) document elements of the Ovarian Cancer Pan-Canadian Standards Data Elements (OCPCDE) check...

Can circulating cell free DNA be a promising marker in ovarian cancer? - a genome-scale profiling study in a single institution.

Jan 16, 2023

Cell-free DNA (cfDNA) is emerging as a potential biomarker for the detection of ovarian cancer (OC). Recently, we reported a method based upon cfDNA whole-genome sequencing data including the nucleoso...

Prophylactic Salpingectomy during Hysterectomy for Benign Disease: A Prospective Study to Evaluate High-Grade Serous Ovarian Carcinoma Precursors.

Jan 09, 2023

Recent findings suggest that high-grade serous ovarian cancer can originate in the fallopian tube. Not only has that made the identification of precursor lesions pivotal in early detection and prevent...

Targeted Delivery of Sunitinib by MUC-1 Aptamer-Capped Magnetic Mesoporous Silica Nanoparticles.

Jan 09, 2023

Magnetic mesoporous silica nanoparticles (MMSNPs) are being widely investigated as multifunctional novel drug delivery systems (DDSs) and play an important role in targeted therapy. Here, magnetic cor...

Cancer antigen 125 expression enhances the gemcitabine/cisplatin-resistant tumor microenvironment in bladder cancer.

Jan 02, 2023

Cancer antigen 125 (CA125) is one of the mucin family proteins and is a serum tumor marker for various tumors, such as ovarian cancer, endometrial cancer, pancreatic cancer, and bladder cancer, used t...

The prognosis predictive score around primary debulking surgery (PPSP) improves diagnostic efficacy in predicting the prognosis of ovarian cancer.

Jan 02, 2023

In recent years, the pretreatment inflammatory responses have proven to predict the prognosis, but no report exists analyzing the combined inflammatory response of the pre- and postsurgical treatment....

Integrated multi-omic analysis of low-grade ovarian serous carcinoma collected from short and long-term survivors.

Dec 19, 2022

Low-grade serous ovarian cancer (LGSOC) is a rare disease that occurs more frequently in younger women than those with high-grade disease. The current treatment is suboptimal and a better understandin...

Pretreatment Nutritional Status in Combination with Inflammation Affects Chemotherapy Interruption in Women with Ovarian, Fallopian Tube, and Peritoneal Cancer.

Dec 12, 2022

Discontinuing chemotherapy worsens cancer prognosis. This study aimed to investigate the relationship between nutritional status at the start of chemotherapy and chemotherapy discontinuation in patien...

Fertility Options for Patients With Gynecological Cancer

Nov 04, 2022

For patients with early-stage endometrial cancer (EC), standard treatment has been hysterectomy with bilateral salpingo-oophorectomy with lymphadenectomy, note the authors of a study published in ...

Immune Microenvironment Manipulation for Uterine Cancer

Oct 04, 2022

Studies show that endometrial cancer (EC) rates are increasing in younger people with obesity is a likely contributor to this observed proliferation because it raises estrogen production and adipokine...

Conservative Vs Surgical Management of Atypical Endometrial Hyperplasia

Oct 04, 2022

Endometrial hyperplasia (EH), a known risk factor for endometrial cancer (EC), is an irregular proliferation of the adrenal glands increasing the gland to stroma ratio. If it manifests as atypical end...

Foreseeing Uterine Cancer’s Lymph Node Metastasis (LNM)

Oct 01, 2022

Histopathological criteria have a huge role in the preoperative categorization in endometrial carcinoma (EC). Due to the danger of lymph node metastasis (LNM), the diagnostic performance is moderate. ...

Feasibility of Adjuvant Radiation Therapy to Treat Gynecological Cancer

Oct 01, 2022

Endometrial cancer is a widely recognized female threat. It usually affects around 40,000 women every year. Numerous prospective arbitrary trials have been published. However, despite that, there stil...

MetS Tied to Poor Prognosis in Some Uterine Cancers

Sep 19, 2022

Metabolic syndrome was tied closely to poor prognosis among patients with endometrial cancer, according to a study published in Frontiers in Endocrinology. For the retrospective study—conducted at a...

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