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Ophthalmology General

Intravitreal bevacizumab versus intravitreal triamcinolone for diabetic macular edema-Systematic review, meta-analysis and meta-regression.

Jan 14, 2021

The most frequent cause of vision loss from diabetic retinopathy is diabetic macular edema (DME). Earlier clinical trials tried to examine the role of intravitreal triamcinolone (IVT) and intravitreal...

Assessment of ocular surface disease in glaucoma patients with benzalkonium chloride-preserved latanoprost eye drops: a short-term longitudinal study.

Jan 14, 2021

To prospectively evaluate the effect of benzalkonium chloride (BAK)-preserved latanoprost on ocular surface damage and identify the associated risk factors among treatment-naive glaucoma patients.The ...

Regulation of distinct caspase-8 functions in retinal ganglion cells and astroglia in experimental glaucoma.

Jan 14, 2021

Retinal ganglion cells (RGCs) expanding from the retina to the brain are primary victims of neurodegeneration in glaucoma, a leading cause of blindness; however, the neighboring astroglia survive the ...

The Distribution of Retinal Venous Pressure and Intraocular Pressure Differs Significantly in Patients with Primary Open-Angle Glaucoma.

Jan 14, 2021

Until now, venous pressure within the eye has widely been equated with intraocular pressure (IOP). Measurements with dynamometers calibrated in instrument units or in force showed that the retinal ven...

Deployment of the Ophthalmic and Facial Angiosomes in the Upper Nose Overlaying the Nasal Bones.

Jan 11, 2021

Nasal filler placement is associated with a high risk of blindness. The arterial supply to the upper nose overlaying the nasal bones is poorly understood.This study attempts to visualize and analyze t...

Behçet disease, New insights in disease associations and manifestations. A next generation sequencing study.

Jan 11, 2021

Behçet disease is a multisystem disease associated with Human Leucocyte Antigen (HLA) class I polymorphism. High-resolution Next Generation Sequencing (NGS) with haplotype analysis has not been perfo...

Vector Analysis of Visual Acuity and Refractive Outcomes of Astigmatic Corrections After T-PRK and Fs-LASIK.

Jan 11, 2021

T Transepithelial photorefractive keratectomy (T-PRK) and femtosecond laser in situ keratomileusis (Fs-LASIK) are reftactive surgery methods for treating myopia and myopic astigmatism. Although T-PRK ...

Comparison of Methods for Estimating Retinal Shape: Peripheral Refraction vs. Optical Coherence Tomography.

Jan 11, 2021

Retinal shape presents a clinical parameter of interest for myopia, and has commonly been inferred indirectly from peripheral refraction (PRX) profiles. Distortion-corrected optical coherence tomograp...

Anterior scleral thickness and shape changes with different levels of simulated convergence.

Jan 11, 2021

Convergence plays a fundamental role in the performance of near visual tasks. We measured the effect of two levels of convergence on anterior scleral thickness and shape in emmetropes, low to moderate...

Impact of comorbid Sjögren syndrome in anti-aquaporin-4 antibody-positive neuromyelitis optica spectrum disorders.

Jan 11, 2021

Neuromyelitis optica spectrum disorders (NMOSD) are autoimmune neurological diseases of the central nervous system, which are characterized by the presence of serum anti-aquaporin-4 autoantibodies (AQ...

Randomised assessormasked trial evaluating topical manuka honey (Optimel) in treatment of meibomian gland dysfunction.

Jan 11, 2021

To evaluate the effects of manuka honey eye-drops in the treatment of meibomian gland dysfunction.This is an assessor-masked (single-blind), randomised controlled trial comparing conventional treatmen...

The relationship between dry eye and sleep quality.

Jan 11, 2021

Sleep is an important determinant of health and quality of life. This study aimed to clarify the association between dry eye and sleep quality using a large population-based cohort.71,761 participants...

Efficacy of bevacizumab for vitreous haemorrhage in proliferative diabetic retinopathy with prior complete panretinal photocoagulation.

Jan 11, 2021

To investigate the efficacy of intravitreal bevacizumab injections (IVBs) for vitreous haemorrhage (VH) in proliferative diabetic retinopathy (PDR) with prior complete panretinal photocoagulation (PRP...

Contextualising Single-Arm Trials With Real-World Data: An Emulated Target Trial Comparing Therapies For Neovascular Age-Related Macular Degeneration.

Jan 11, 2021

One-in-four ophthalmology trials are single-armed, which poses challenges to their interpretation. We demonstrate how real-world cohorts used as external/synthetic control arms can contextualise such ...

Development of a zebrafish screening model for diabetic retinopathy induced by hyperglycemia: Reproducibility verification in animal model.

Jan 11, 2021

This study aimed at creating a zebrafish screening model for diabetic retinopathy, and evaluated the effects of aflibercept, which is being used to treated diabetic retinopathy. A morphological change...

Causes of corneal transplant failure: a multicentric study.

Jan 11, 2021

To identify the causes of failure of the different surgical corneal graft techniques: penetrating keratoplasty (PK), deep anterior lamellar keratoplasty (DALK), Descemet stripping automated endothelia...

Cost-effectiveness of dexamethasone and triamcinolone for the treatment of diabetic macular oedema in Finland: A Markov-model.

Jan 11, 2021

Diabetic macular oedema (DMO), a complication of diabetes, causes vision loss and blindness. Corticosteroids are usually used as a second-line treatment. The aim of this study was to analyse the cost-...

Prevalence of MYOC risk variants for glaucoma in different populations.

Jan 11, 2021

To assess the clinical relevance of myocilin (MYOC) gene variants as risk factors for glaucoma in literature and to estimate their prevalence in different populations.We reviewed the literature for pu...

Unilateral lateral rectus recession is an effective surgery for intermittent exotropia in young children.

Jan 11, 2021

Different surgical methods have been suggested for the correction of intermittent exotropia. Unilateral lateral rectus recession has been described as a surgical alternative for small and moderate-ang...

Evaluation of a Home-Printable Vision Screening Test for Telemedicine.

Jan 11, 2021

Many ophthalmology appointments have been converted to telemedicine assessments. The use of a printed vision chart for ophthalmology telemedicine appointments that can be used by people who are exclud...

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