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Aging

#PWChat Recap: The Complexities of Dementia Care

Jul 12, 2021

The latest installment of the #PWChat series centered around trends in continuing medical education. Below are the highlights from the chat. You can read the full transcript here, by scrolling th...

Influence of radiation conditions on the wear behaviour of Vitamin E treated UHMWPE gliding components for total knee arthroplasty after extended artificial aging and simulated daily patient activities.

Jul 12, 2021

The long term performance of total knee arthroplasty (TKA) with regards to the bearing materials is related to the aging behaviour of these materials. The use of highly crosslinked materials in hip ar...

Protective effect of taurine on UVB-induced skin aging in hairless mice.

Jul 12, 2021

Taurine, a sulfur-containing amino acid derivative, exists at a high concentration in the skin and is considered to play an important role in maintaining moisture homeostasis. This study investigated ...

Physical exercise increases global and gene-specific (IL-17 and IFN-gamma) DNA methylation in lymphocytes from aged women.

Jul 08, 2021

What is the central question of this study? Is lymphocyte DNA methylation differentially modulated by resistance training and aerobic exercise in older women? What are the main finding and its importa...

A bibliometric analysis of publications on COVID-19 and older adults.

Jul 08, 2021

Bibliometric analysis is important to guide future research priorities. We aimed to evaluate the most relevant scientific research on COVID-19 and older adults, analyze the current hot topics and iden...

Primary emissions and secondary production of organic aerosols from heated animal fats.

Jul 05, 2021

Cooking is an important source of primary organic aerosol (POA) in urban areas, and it may also generate abundant non-methane organic gases (NMOGs), which form oxidized organic aerosol (OOA) after atm...

1,4-dihydropyridine derivatives increase mRNA expression of , , and in rats.

Jul 01, 2021

The ubiquitin-proteasome system modifies different cellular and protein functions. Its dysregulation may lead to disrupted proteostasis associated with multiple pathologies and aging. Pharmacological ...

Heavy metal remediation by nano zero-valent iron in the presence of microplastics in groundwater: Inhibition and induced promotion on aging effects.

Jun 28, 2021

Nano zerovalent iron (nZVI) is one of the most broadly applied nanomaterials in the fields of groundwater remediation which benefits from its high reactivity for pollutants. However, its successful ap...

Age does not affect the relationship between muscle activation and joint work during incline and decline walking.

Jun 28, 2021

Older compared with younger adults walk with different configurations of mechanical joint work and greater muscle activation but it is unclear if age, walking speed, and slope would each affect the re...

Experiences With Social Participation in Group Physical Activity Programs for Older Adults.

Jun 28, 2021

Little is known about how social participation can be facilitated among older adults in group physical activity and its psychosocial benefits that contribute to successful aging. This study aimed to u...

Multiplatform metabolomics for an integrative exploration of metabolic syndrome in older men.

Jun 24, 2021

Metabolic syndrome (MetS), a cluster of factors associated with risks of developing cardiovascular diseases, is a public health concern because of its growing prevalence. Considering the combination o...

Current knowledge about the connection between health status and gut microbiota from birth to elderly. A narrative review.

Jun 24, 2021

The human body is colonized from the birth by a large number of microorganisms. This will constitute a real "functional microbial organ" that is fundamental for homeostasis and therefore for health in...

A detailed review of the outbreak of COVID-19.

Jun 24, 2021

The disease COVID-19 caused by SARS-CoV-2 is the third highly infectious human Coronavirus epidemic in the 21 century due to its high transmission rate and quick evolution of its pathogenicity. Genomi...

Age-dependent modulation of motor network connectivity for skill acquisition, consolidation and interlimb transfer after motor practice.

Jun 17, 2021

Age-related differences in neural strategies for motor learning are not fully understood. We determined the effects of age on the relationship between motor network connectivity and motor skill acquis...

Circulating microRNA profile in humans and mice with congenital GH deficiency.

Jun 14, 2021

Reduced inflammation, increased insulin sensitivity, and protection against cancer are shared between humans and mice with GH/IGF1 deficiency. Beyond hormone levels, miRNAs are important regulators of...

Mind-body Practices and Cognitive Function in Middle-Aged and Older Adults: Findings from the Midlife in the United States (MIDUS) Study.

Jun 14, 2021

Cognitive function is a key component of healthy aging. While conventional physical activities (walking, jogging, etc.) have been shown to support health in late-life, including cognitive health, it r...

Factors and Outcomes of Intensive Care Unit Readmission in Elderly Patients.

Jun 10, 2021

An increase in age has been observed among patients admitted to the intensive care unit (ICU). Age is a well-known risk factor for ICU readmission and mortality. However, clinical characteristics and ...

Blood Oxygen Carrying Capacity Determines Cardiorespiratory Fitness in Middle-Age and Older Women and Men.

Jun 10, 2021

Whether blood oxygen (O2) carrying capacity plays a substantial role in determining cardiorespiratory fitness, a strong predictor of mortality, remains uncertain in women and elderly individuals due t...

Assessment of cube-copying among community-dwelling elderly living in Japan using the vertex criterion and parallelism.

Jun 10, 2021

The cube-copying test is used to assess cognitive function. It is one of the methods used to distinguish healthy older individuals from those with cognitive impairment based on its 3 mm vertex crite...

Coping and healthcare utilization in LGBTQ older adults: A systematic review.

Jun 07, 2021

This systematic review was conducted to identify, synthesize, and elucidate the coping mechanisms described by aging lesbian, gay, bisexual, transgender, and queer (LGBTQ) adults (60+) when utilizing ...